Radiation therapy continues to have a major therapeutic role in the treatment of breast cancer. Radiation therapy in combination with lumpectomy and axillary dissection has been standard therapy for early-stage disease since the 1970s. There has been increasing interest recently in the use of postmastectomy radiation. A number of areas of controversy surround which patients will benefit from po...

Radiation therapy continues to have a major therapeutic role in the treatment of breast cancer. Radiation therapy in combination with lumpectomy and axillary dissection has been standard therapy for early-stage disease since the 1970s. There has been increasing interest recently in the use of postmastectomy radiation. A number of areas of controversy surround which patients will benefit from po...

Despite wide efforts for early detection of breast cancer using screening mammography, locally advanced breast carcinomas account for a remarkable proportion of all breast carcinomas, particularly in developing countries. Locally advanced breast cancer may have widely different clinical and biological features. Radiotherapy plays an important role in the management of locally advanced breast ca...

Radiation therapy is an integral part of the multimodality treatment of breast cancer and in the recent years, there has been increasing evidence from prospective randomized trials and large meta-analyses supporting greater utilization of radiation therapy for patients at high risk for local-regional relapse after mastectomy [1]. Today, there is broad consensus on indications for postmastectomy...

Radiation therapy continues to have a major therapeutic role in the treatment of breast cancer. Radiation therapy in combination with lumpectomy and axillary dissection has been standard therapy for early-stage disease since the 1970s. There has been increasing interest recently in the use of postmastectomy radiation. A number of areas of controversy surround which patients will benefit from po...

Purpose: To identify genes predicting benefit of radiotherapy in patients with high-risk breast cancer treated with systemic therapy and randomized to receive or not receive postmastectomy radiotherapy

An asthmatic patient requiring corticosteroid treatment developed a pulmonary aspergilloma in an area of postmastectomy radiation fibrosis. At necropsy bronchocentric granulomatosis was also found.

BACKGROUND At a time when the safety and effectiveness of breast implants remains under close scrutiny, it is important to provide reliable and valid evidence regarding patient outcomes. In the setting of postmastectomy reconstruction, patient satisfaction and quality of life may be the most significant outcome variables when evaluating surgical success. The objective of the current study was t...