Orally disintegrating tablets (ODTs) are capable of turning quickly into a liquid dosage form in contact with the saliva, thus possessing the advantages of both the solid dosage forms particularly stability and liquid dosage forms specially ease of swallowing and pre-gastric absorption of drug. The aim of this study was to prepare a novel matrix-type buccal fast disintegrating ibuprofen tablet ...

orally disintegrating tablets (odt) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. we focused on taste masking and formulation of ranitidine odt which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Development of new oral cyclosporine formulation using cyclodextrin tetrapolymer (Pαβγ-CD) in attempt to enhance its stability and dissolution rate.Two spray-dried dispersion formulations containing poorly water-soluble cyclosporine (CsA) were prepared with cyclodextrin tetrapolymer in water (FH2O) and ethanol (FEOH) then characterized by scanning electron microscopy, powder X-ray diffraction, ...

Piroxicam is a poorly soluble, highly permeable drug and is characterized by a slow and gradual absorption via the oral route and this causes a delayed onset of therapeutic effect. Thus, plain piroxicam preparations are not indicated for analgesia. The results of the in vivo study revealed that the GL dosage form would be advantageous with regards to rapid onset of action, especially in various...

background: every year many organizations formulate a code of ethics (coe) but when it comes to implementing, it does not achieve the desired purposes. ineffectiveness of coes can stem from different factors and surely, one of them is bad formulation. this research was conducted to identify the barriers to effective formulation of coes in one of the main state universities of medical sciences i...

Abstract Levetiracetam as an Anti-epileptic drug with exclusive mechanism of action is accepted by the USA Food and Drug Administration as an adjunctive therapy in treating epilepsy in young adults. The purpose of this project is the design and formulation of prolonged release of levetiracetam using two types of retarding agent such as Hydroxyl Propyl Methylcellulose (HPMC K4...

the mating disruption technique has been widely used for the control of several lepidopteran pests. in the present study, we assessed the efficiency of two formulations of splat neo, a wax emulsion containing e-11-hexadecenol, with and without the insecticide cypermethrin, in affecting mating disruption of neoleucinodes elegantalis (guenée). we also determined the best phenological age or stage...