This study tests the feasibility of applying the pragmatic-explanatory continuum indicator summary (version "PRECIS-2") tool to randomized controlled trials of Chinese herbal medicine. A search was conducted to identify potentially eligible randomized controlled trials. Using the PRECIS-2 tool, assessment of trials was performed independently by 2 evaluators using a scale of 1-5 for each criter...

BACKGROUND There continues to be debate about what constitutes a pragmatic trial and how it is distinguished from more traditional explanatory trials. The NIH Pragmatic Trials Collaborative Project, which includes five trials and a coordinating unit, has adopted the Pragmatic-Explanatory Continuum Indicator Summary (PRECIS-2) instrument. The purpose of the study was to collect PRECIS-2 ratings ...

BACKGROUND The National Institutes of Health (NIH) Health Care Systems Research Collaboratory (NIH Collaboratory) seeks to produce generalizable knowledge about the conduct of pragmatic research in health systems. This analysis applied the PRECIS-2 pragmatic trial criteria to five NIH Collaboratory pragmatic trials to better understand 1) the pragmatic aspects of the design and implementation o...

We present the CR-precis structure, that is a general-purpose, deterministic and sub-linear data structure for summarizing update data streams. The CR-precis structure yields the first deterministic sub-linear space/time algorithms for answering a variety of fundamental queries over update streams, such as, (a) point queries, (b) range queries, (c) finding approximate frequent items, (d) findin...

We present the CR-precis structure, that is a general-purpose, deterministic and sub-linear data structure for summarizing update data streams. The CR-precis structure yields the first deterministic sub-linear space/time algorithms for update streams for answering a variety of fundamental stream queries, such as, (a) point queries, (b) range queries, (c) finding approximate frequent items, (d) ...

Papers published in Hydrology and Earth System Sciences Discussions are under open-access review for the journal Hydrology and Earth System Sciences Abstract The most important climatological inputs required for the calibration and validation of hydrological models are temperature and precipitation that can be derived from observational records or alternatively from regional climate models (RCM...

BACKGROUND Pragmatic clinical trials (PCTs) are increasingly recommended to evaluate interventions in real-world conditions. Although PCTs share a common approach of evaluating variables from actual clinical practice, multiple characteristics can differ. These differences affect interpretation of the trial. The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model was developed in 20...

Regional climate models (RCMs) are considered to be more useful than general circulation models for assessing impacts of climate change scenarios in agriculture. In this communication, the climatic outputs of an RCM–PRECIS (providing regional climates for impact studies) model were analysed by comparing its baseline simulation daily weather data on temperature and precipitation patterns with th...