نتایج جستجو برای: predictive biomarker
تعداد نتایج: 196512 فیلتر نتایج به سال:
background : the measuring serum ferritin level as a sensitive inflammatory biomarker might effectively predict preterm delivery, but the power and the best cut-off point of this biomarker for predicting preterm labor in iranian population has not been substantially identified. our purpose was to determine what concentrations of serum ferritin could identify patients at risk for preterm deliver...
Background: Recent biotechnological developments have resulted in increasing interest in immunology biomarkers. These biomarkers have potential clinical utility in the near future as predictors of treatment response. Hence, clinical validation of these predictive markers is critical. Findings: The process of clinically validating a predictive biomarker is reviewed. Validation of a predictive bi...
BACKGROUND Recent biotechnological developments have resulted in increasing interest in immunology biomarkers. These biomarkers have potential clinical utility in the near future as predictors of treatment response. Hence, clinical validation of these predictive markers is critical. FINDINGS The process of clinically validating a predictive biomarker is reviewed. Validation of a predictive bi...
We study information theoretic methods for ranking biomarkers. In clinical trials, there are two, closely related, types of biomarkers: predictive and prognostic, and disentangling them is a key challenge. Our first step is to phrase biomarker ranking in terms of optimizing an information theoretic quantity. This formalization of the problem will enable us to derive rankings of predictive/progn...
There is growing recognition that immunotherapy is likely to significantly improve health outcomes for cancer patients in the coming years. Currently, while a subset of patients experience substantial clinical benefit in response to different immunotherapeutic approaches, the majority of patients do not but are still exposed to the significant drug toxicities. Therefore, a growing need for the ...
We describe work aimed at cost-constrained knowledge discovery in the biomedical domain. To improve the diagnostic/prognostic models of cancer, new biomarkers are studied by researchers that might provide predictive information. Biological samples from monitored patients are selected and analyzed for determining the predictive power of the biomarker. During the process of biomarker evaluation, ...
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