this research proposes an efficient and easy procedure for the preparation of amides or nitriles from aldehydes. such materials were prepared via one-pot three component condensation reaction of various aldehydes in the presence of nano-ticl4.sio2 as a catalyst under thermal conditions. all reactions proceeded in high yields and in a moderately short reaction time. meanwhile, oximes were obtain...

Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.

Nitrile is a functional group that usually is transformed to amides or carboxylic acids under strong reaction conditions in acidic or basic media and high temperatures. Amides have also been prepared from nitriles at room temperature using strong oxidizing agents such as hydrogen peroxide or sodium superoxide in DMSO. On the other hand biocatalytic hydrolysis of nitriles mediated by nitrilase, ...

A. Introduction B. Acid-Catalysed Esterification and Transesterification 1. General mechanism 2. Methanolic hydrogen chloride 3. Methanolic sulfuric acid 4. Boron trifluoride-methanol 5. Other acidic catalysts C. Base-Catalysed Transesterification 1. General mechanism 2. Sodium and potassium methoxide catalysts 3. Organic base catalysis D. Diazomethane and Related Reagents 1. Diazomethane and m...

We describe the first gram scale preparation of the reagent dichlorotrifluoromethoxyacetic acid. This stable compound is obtained in five steps starting from the cheap diethylene glycol. The reactivity of the sodium salt of this fluorinated acid was also tested and allowed the preparation of new amides.

A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles.

Aggregates of perylene bisimide (PBI) derivative 3 serve as reactors and stabilizers for the preparation of mercury nanoparticles (HgNPs) which exhibit excellent catalytic efficiency in the conversion of aldoximes/ketoximes into primary/secondary amides via Beckmann rearrangement.