OBJECTIVES To assess the effects on dry eye symptoms and tear dynamics of switching from a prostaglandin with a preservative to a preservative-free prostaglandin. MATERIAL AND METHODS Fourteen patients (N=28 eyes) with open-angle glaucoma and dry eye symptons, treated with preserved latanoprost, travoprost or bimatoprost were included in this uncontrolled prospective study. Ocular symptoms we...

Aims: To clarify the usefulness of preservative-free ophthalmic preparations equipped with a filter. Methods: A total of 1,615 samples of in-use ophthalmic preparations were examined for microbial contamination. Results: Of 1,094 samples of preservative-containing ophthalmic preparations, 31 (2.8%) showed microbial contamination. Of 289 samples of preservative-free ophthalmic preparations witho...

OBJECTIVES This randomized, double-blind, cross-over study evaluated the risk of bronchoconstriction with two preparations of inhaled tobramycin in children with cystic fibrosis (CF) infected with Pseudomonas aeruginosa with and without airway hyperreactivity. DESIGN Of 19 children with CF (age range, 7 to 16 years) with mild-to-moderate pulmonary disease, 10 children were at high risk (HR) f...

Preservative treatment of wood has a long history in the United States and throughout the world. Even the early settlers to the New World in the 17th century used wood preservatives to protect homes and other structures. The treated wood industry in the United States is evolving as new products emerge, technology advances, and environmental concerns increase. Recently, chromated copper arsenate...

PURPOSE The toxicity of antiglaucoma medications to ocular surface cells has been evaluated extensively; however, the toxicity to corneal endothelial cells (CECs) remains elusive. Our aim is to evaluate the toxicity of antiglaucoma medications to CECs using an in vitro toxicity assay. METHODS Primary cultures of human (H) CECs derived from eye bank specimens were established. Following exposu...

Benzalkonium chloride, a surface-active preservative commonly used in eyedrop preparations, has been shown to hasten the drying of the precorneal tear film. In the rabbit, 0.01 per cent benzalkonium (the concentration usually employed as a preservative) shortened the time required for the appearance of dry spots on the corneal surface by a factor of about four. In man, an approximately twofold ...

Since high quality forage is essential in a dairy ration, it is improtant to study new methods of preserving hay. In this trial, the effect of a commercial organic acid preservative on nutirent content and feeding value of alfalfa hay was evaluated. Alfalfa hay from a common field was baled at about 20 percent moisture for a control, and at about 28 percent moisture with addition of 0.1 percent...