ocular surface may be involved by different neoplastic lesions ranging from benign to highly malignant. recognition of risk factors, clinical presentations, pathology, and different therapeutic modalities is essential for selecting an appropriate approach. this article deals with the proper approach to ocular surface squamous neoplasia (ossn) including conjunctival/corneal intraepithelial neopl...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...

squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. most of the reported cases have had a component of adenocarcinoma. we report a 70-year-old man who presented with acute onset right upper quadrant pain. he operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. histop...

zinc has an important role in skin health and its deficiency reduces immunity. to evaluate levels of zinc in squamous cell carcinoma (scc) and basal cell carcinoma (bcc) of skin, we studied 44 bcc and 38 scc cases together with 33 controls. blood samples were taken and after separation of serum, levels of zinc, albumin and total protein were measured by atomic absorption, albumin kit and reflec...

background and aims. there is no report on the apoptotic impact of allium sativum l. (garlic) on the oral squamous cell carcinoma (kb); hence, this study was designed to survey the apoptotic effects of garlic fresh juice (gfj) on the kb cells. materials and methods. mtt assay (microculture tetrazolium assay) was carried out to evaluate the cytotoxicity of gfj on kb cells. furthermore, tunel (te...

â  â  background esophageal squamous cell carcinoma (escc) is usually detected in advanced stages resulting in a very poor prognosis. early diagnoâ­sis needs identification of clinically relevant precancerous lesions which could become the target of screening and early treatment. our aim was to check whether esophagitis could serve as a relevant histological precursor of escc in northern iran. ...

background and aims. several diagnostic methods are being employed to detect benign and malignant lesions, one of which is silver nitrate staining for organizer regions. the number of nucleolar organizing regions (nors) can be used to show the degree of cell activity or metabolism in pathologic lesions. this study was designed to evaluate nors as determinants of precancerous and squamous cell c...

conclusions based on evidence, dentists and dental health care professionals should consider periodontal disease as a risk factor for the development of neoplasms in the oral cavity. it also seems a good idea to provide periodontal therapy for patients with cancer to achieve ideal therapeutic results. results cancer of the oral cavity and periodontal disease are related from different aspects. ...

Background: Oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ING1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. Transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. The objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

background and objective: cutaneous cytology is the study of scraping or smears obtained from skin lesions. although not commonly employed, cutaneous cytology has been a useful tool for clinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of common types of skin tumors. this investigation was conducted to study usefulness of cutaneous cy...