Purpose. To analyze the outcomes and difference after UVA/riboflavin corneal collagen crosslinking (CXL) in four different corneal thickness groups of patients with progressive keratoconus. Methods. Retrospective study. Eyes with progressive keratoconus after CXL were divided into 4 subgroups as follows: group 1, thinnest corneal thickness (TCT) ≤ 400 µm; group 2, 400 µm < TCT ≤ 450 µm; group 3...

INTRODUCTION Keratoconus is a progressive and non-inflammatory ectasia of the cornea, mostly bilateral causing low vision because of the irregular astigmatism. The influence of the disease on quality of life is dependent on limiting factors and personality type. PURPOSE To verify quality of life and personality type of the person with keratoconus. METHODS Sixty-eight individuals with kerato...

Keratoconus has been recognized and investigated for more than 150 years (1). Historically, ophthalmologists have described keratoconus as a bilateral, progressive, non-inflammatory disorder of the cornea that is associated with corneal steepening and thinning (1,2). The Global Panel on Keratoconus and Ectatic Diseases recently stated that ‘abnormal posterior ectasia, abnormal corneal thickness...

Purpose To describe a new technique to deliver riboflavin into the corneal stroma during Corneal Cross-Linking (CXL) without removal of epithelium. Methods Keratoconus patients underwent CXL for progressive keratoconus. Riboflavin was delivered by manually creating an epithelial pocket (CXL Epi-Pocket). Verbal rating scale recorded postoperatively. Best-corrected visual acuity, keratometric ind...

To the Editor: Bak-Nielsen et al. recently reported on the dynamic assessment of keratoconus and the effects of corneal cross-linking (CXL).1 The authors described the corneal deformation during rapidly applied force via an air jet using ultra high-speed Scheimpflug technology (Corvis ST; Oculus Optikgeräte GmbH, Wetzlar, Germany).1 Patients with both untreated and CXL-treated keratoconus were ...

Keratoconus is a bilateral, non-inflammatory, degenerative corneal disease. The occurrence and development of keratoconus is associated with corneal thinning and conical protrusion, which causes irregular astigmatism. With the disruption of the collagen organization, the cornea loses its shape and function resulting in progressive visual degradation. Currently, corneal topography is the most im...

In this work, the authors presented the techniques and the preliminary results at 6 months of a randomized controlled trial (NCT02117999) comparing a novel transepithelial corneal cross-linking protocol using iontophoresis with the Dresden protocol for the treatment of progressive keratoconus. At 6 months, there was a significant average improvement with an average flattening of the maximum sim...

Keratoconus is a bilateral, asymmetrical, non-inflammatory, progressive disease, which induces a conical cornea and visual impairment because of biomechanical changes (1). Keratoplasty is an effective method for this ectatic corneal disorder, however, donor cornea is devoid seriously especially in Asia including China. Conservative treatment approaches could not prevent deterioration of the con...

Pellucid marginal degeneration (PMD) is a rare progressive condition resulting in inferior corneal thinning and astigmatism. Alongside keratoconus and keratoglobus, it is considered one of noninflammatory corneal ectasias. The focus of corneal thinning is greatest inferiorly resulting in diminished visual acuity and overall reduction in visual quality. Traditional methods of treatment or diseas...