The metabolism of plasticizing phthalates may correlate with an increased risk benign prostatic hyperplasia in humans. Diethylphthalate (DEHP) and its metabolites interfere sex hormone function, causing inflammation oxidative stress at low doses. effects contribute to the development prostate hyperplasia.

background prostate is an important male reproductive system gland and its disorders can affect men's quality of life and health. prostatitis, benign prostatic hyperplasia (bph), and prostate adenocarcinoma are major disorders that can be found in all men in different ages. objectives the aim of this study was to investigate the association of diet with serum prostate specific antigen (psa) lev...

perforin(p) is the primary mediator of short term cytotoxicity, it is accumulated in response to proinflammatory  cytokines and stored in t lymphocyte , nk cells and nkt cells are released upon activation. perforin is a prototypical cytotoxic molecule involved in cell mediated immunity against various pathogens , alloantigens and particularly different tumors.the purpose of this study was to de...

benign prostatic hyperplasia (bph) is the most common condition in aging men, associated with lower urinary tract symptoms. it is caused due to the augmented levels of the androgen dihydrotestosterone. dutasteride, a 5α-reductase inhibitor has been recommended for the treatment of bph upon oral administration. however, long term oral administration of dutasteride may cause sexual problem in man...

background : a single nucleotide variation within  atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...

Objective: To evaluate the correlation of International Prostatic Symptom Score with Prostate Volume Benign Hyperplasia patients. Study Design: A Cross- out sectional study was done. Qualitative variables measured by Chi square test and quantitative ANOVA. Pearson & multinominal regression were applied. P value considered significant at <0.05. It conducted in a tertiary care hospital, Zi...

Thirty cases of benign prostatic hyperplasia and 30 cases of prostatic adenocarcinoma were selected and stained by AgNOR (argyrophilic staining of the nucleolar organizer region) method. Specimens were obtained by either prostatectomy (open!TIJR) or needle biopsy of the prostate. In this study, the sections of prostatic adenocarcinoma were reviewed. 6 cases were diagnosed as well-differen...

: Benign prostatic hyperplasia (BPH) is the overgrowth of prostate tissues with high prevalence in older men. BPH pathogenesis is not completely understood, but it is believed to be a result of de novo overgrowth of prostatic stroma. In this study, we show that aberrant activation of transforming growth factor-β (TGF-β) mobilizes mesenchymal/stromal stem cells (MSCs) in circulating blood, which...

Old intact male dogs are often predisposed to benign prostatic hyperplasia. Both hypertrophy and hyperplasia of prostate gland occur due to hormonal influences. Clinical signs such as haematuria, stranguria and tenesmus are often associated with benign prostatic hyperplasia. A seven year-old local breed intact male dog was presented with a primary complaint of haematuria and stranguria. Diagnos...

Background: Benign Prostatic Hyperplasia is a common condition in the elderly population. It affects physical health status persons over 65 years and interferes with their daily activities. Study Aim: to assess knowledge care seeking behaviors among old age patients hyperplasia Sample: aged 60 above diagnosed benign prostatic hyperplasia. The total sample size was 218 elderly. Cross-sectional r...