نتایج جستجو برای: protein sequencing

تعداد نتایج: 1336591  

M. Tahmoorespur, M.H. Sekhavati T. Abbassi-Daloii

Brucellosis is caused by the bacterium Brucella and affects various domestic and wild species. GroEL (Heat Shock Protein 60kDa) as one of the major antigens that stimulate the immune system, increases Brucella survival. The aim of the current study was to clone and express GroEL in Escherichia coli in order to design subunit vaccine. Amplifying was performed using specific primers. The full-len...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم بهزیستی و توانبخشی - دانشکده زیست شناسی 1392

ناتوانی ذهنی رایج ترین ناهنجاری تکاملی در انسان است. شیوع این بیماری با در نظر گرفتن جمعیت های مختلف 1-3% می باشد. این بیماری به علل گوناگون از جمله عوامل محیطی و ژنتیکی ایجاد می شود، که عوامل ژنتیکی نقش بسزایی در ایجاد آن دارد. عقب ماندگی ذهنی به دو نوع سندرمی و غیرسندرمی تقسیم بندی می شود. در این تحقیق سعی بر آن است که علل ژنتیکی در خانواده های ایرانی که دارای فرزند یا فرزندان مبتلا به عقب ما...

Kianifard D Mousavi Z, Rezaee F

Background: Male infertility has many causes, including genetic infertility. The NOP2/Sun domain family, member7 (Nsun7) gene, which encodes putative methyltransferase Nsun7, has a role in sperm motility. The aim of the present study was to investigate the effect of the T26248G polymorphism on Nsun7 protein function and its role in male infertility. Materials and Methods: Semen samples were col...

Hosseinzadeh Colagar A Khosronezhad N, Mortazavi SM

Background: Male infertility has many causes, including genetic infertility. The NOP2/Sun domain family, member7 (Nsun7) gene, which encodes putative methyltransferase Nsun7, has a role in sperm motility. The aim of the present study was to investigate the effect of the T26248G polymorphism on Nsun7 protein function and its role in male infertility. Materials and Methods: Semen samples were col...

Journal: :Biochem 2022

It is commonly understood that RNA-binding proteins crucially determine the fate of their target RNAs. Vice versa, RNAs are becoming increasingly recognized for functions in protein regulation and dynamics RNA-protein complexes. Long non-coding emerging as potent regulators exert unknown properties moonlighting functions. A vast array RNA- protein-centric techniques have been developed identifi...

Journal: :international journal of health studies 0
somaye malmir 1 1. biotechnology research center, baqiyatallah university of medical science, tehran , iran. ali zarei mahmodabadi 1 masoomeh masoomikarimi 2 2. dept. of basic science, torbat heydariyeh university of medical science, torbat heydariyeh, iran. soheilaalsadat mirhoseini ardakani 3 3. dept. of biology, school of basic sciences, karaj branch, islamic azad university, alborz, iran. elmira roshaniasl 4 4. dept. of biochemistry, school of medicine, uremia university of medical sciences, uremia, iran. shahnaz shekarforoush 3

background: angiogenesis is an important process in various physiologic and pathologic states. the most significant stimulator of angiogenesis is vascular endothelial growth factor (vegf). in contrast, vasohibin1 acts as an angiogenesis inhibitor which specifically inhibits new vessels formation. the aim of the present study was cloning and expression of vasohibin1 gene in e. coli as well as pu...

ژورنال: پژوهش در پزشکی 2010
تقی پور , نیلوفر, حقیقی, علی, سید طبایی , سیدجواد, کاظمی , بهرام, راستی, سیما , نکوئیان , شهرام ,

Abstract Backgraound: Entamoeba histolytica antigenic markers such as Serine-Rich E. histolytica protein (SREHP) have recently been used for vaccine preparation, genetic diversity studies of Entamoeba histolytica isolates and for differentiation between E. histolytica and E. dispar species. This study was carried out with the aim of expression of a recombinant Serine Rich E. histolytica prot...

Journal: :iranian journal of basic medical sciences 0
jamshid faghri department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran kamran pooshang bagheri department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran delavar shahbaz zadeh department of biotechnology, pasteur institute of iran, tehran, iran rahmatolah yazdani department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran hamid mirmohammad sadeghi department of biotechnology, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran sharareh moghim department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran

objective(s) staphylococcus aureus is a leading cause of many nosocomial and community acquired infections. according to many reports, antibiotic therapy can not guarantee the eradication of s. aureus infections. thus designing an adhesin based vaccine could restrain the s. aureus infections. this study designed for construction of a new fusion protein vaccine against s. aureus infections based...

ژورنال: :gene, cell and tissue 0
farah talebi department of genetic, faculty of sciences, shahid chamran university of ahvaz, ahvaz, ir iran farideh ghanbari department of genetic, faculty of sciences, shahid chamran university of ahvaz, ahvaz, ir iran; department of genetic, faculty of sciences, shahid chamran university of ahvaz, ahvaz, ir iran. tel/fax: +98-6136233884 javad mohammadi asl department of medical genetics, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

conclusions bioinformatics analyses using sift, mutation taster and polyphen-2 indicated that p.ile563val was predicted to be damaging, disease causing, and probably damaging to and causing ldb3 dysfunction. as such, this mutation produces novel protein coding transcripts, which might explain the mfm phenotype in the patient. introduction myofibrillar myopathy (mfm) is a rare human disease, cha...

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