Introduction: Pseudoexfoliation syndrome (PXS) occurs due to the deposition of extracellular fibrillar materials on the anterior chamber of the eye. This syndrome has been considered to be part of a systemic disease with the potential involvement of the inner ear called sensoroneural hearing loss (SNHL).  In this study, we aimed on evaluating SNHL within PXS patients in Iran to compare them wi...

purpose : to compare central corneal thickness (cct), corneal endothelial cell density, and lens capsule thickness in normotensive patients with and without pseudoexfoliation syndrome (pxs) methods : this was a prospective, comparative, descriptive study. normotensive candidates for cataract surgery with (study group) and without (control group) pxs were enrolled in the study. cct and corneal e...

OBJECTIVE To evaluate the corneal endothelial morphometry and central corneal thickness (CCT) in pseudoexfoliative (PEX) eyes with and without glaucoma and to compare with normal eyes and eyes with primary open-angle glaucoma (POAG). METHOD A total of 166 patients were included in this study: 36 eyes with pseudoexfoliation syndrome (PXS), 30 eyes with pseudoexfoliation glaucoma (PXG), 40 eyes...

Background & Aims: Pseudoexfoliation syndrome (PXS) is a complex disorder which causes an increase in intraocular pressure (IOP). This study was conducted in order to compare IOP of both eyes of patients with unilateral PXS. Methods: In a cross-sectional study from January 2011 to June 2012, 79 patients with unilateral PXS were studied. The patients were examined first with constricted, and the...

introduction: pseudoexfoliation syndrome (pxs) occurs due to the deposition of extracellular fibrillar materials on the anterior chamber of the eye. this syndrome has been considered to be part of a systemic disease with the potential involvement of the inner ear called sensoroneural hearing loss (snhl).  in this study, we aimed on evaluating snhl within pxs patients in iran to compare them wit...

BACKGROUND To quantify the levels of tissue inhibitor of metalloproteinase 4 (TIMP4) and its ratios with free metalloproteinases (MMP) in the aqueous humor of patients with primary open angle glaucoma (POAG), pseudoexfoliation syndrome (PXS) and pseudoexfoliative glaucoma (PXG) and to evaluate a possible imbalance between MMPs and TIMPs in these samples. METHODS Free MMP2, MMP3, MMP9, TIMP1, ...

Background: Pseudoexfoliation syndrome is one of the most common identifiable causes of open angle glaucoma. It has unknown etiology and pathogenesis. Infection, possibly viral, is one of the proposed pathogenic mechanisms in this condition. In the present study the presence of herpes simplex virus (HSV) in specimens of anterior lens capsule of patients with pseudoexfoliation syndrome has been ...

Pseudoexfoliation syndrome is an agerelated disease characterized by the pathological production and accumulation of an abnormal extracellular fibrillar material over ocular tissues as well as other tissues and organs in the body such as the lung, liver, kidney, gall bladder, and cerebral meninges. The specific pathogenesis of pseudoexfoliation syndrome and the exact chemical composition of the...

PURPOSE Pseudoexfoliation syndrome is a major risk factor for the development of glaucoma. Following recent reports of a strong association of coding variants in the lysyl oxidase-like 1 (LOXL1) gene with this syndrome but low penetrance and variable disease frequency between different populations, we aimed to identify additional genetic factors contributing to the disease. The clusterin (CLU) ...