Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in ...

Objective The aim of the current study was to evaluate whether cognitive behavioral group therapy has a positive impact on psychiatric, and motor and non-motor symptoms in Parkinson's disease (PD). Methods We assigned 20 PD patients with a diagnosis of psychiatric disorder to either a 12-week cognitive behavioral therapy (CBT) group or a psychoeducational protocol. For the neurological examin...

This study examines the factor structure of the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) for inpatients with schizophrenia in a psychiatric hospital in southern Taiwan. All the participants (n = 100) filled out the SQLS-R4, Mini Mental Status Examination (MMSE), and Brief Psychiatric Rating Scale (BPRS) under the supervision of one experienced occupational therapist. Using confi...

Quality of life is an important outcome in the treatment of patients with schizophrenia. It has been suggested that patients' quality of life ratings (referred to as subjective quality of life, SQOL) might be too heavily influenced by symptomatology to be a valid independent outcome criterion. There has been only limited evidence on the association of symptom change and changes in SQOL over tim...

For the last 10 years, data have been accumulating indicating that, contrary to former evidence, lithium may play a useful role in the treatment of certain schizophrenic patients. Delva & Letemendia (1982), after reviewing major controlled and uncontrolled studies in this area, concluded that “¿ between one third and one-half of patients with schizophrenia will benefit from lithium―. In two...

chronic  obstructive  pulmonary  disease (copd)  and  asthma  are  major  public  health problems, which seems to have close association with psychiatric disorders. the present study was conducted to compare the psychological status between asthmatic and copd patients and clarify the relationship with severity of pulmonary obstruction. this cross-sectional study was planned to compare the psych...

The authors report the results of a confirmatory factor analysis of symptoms assessed with the Brief Psychiatric Rating Scale (BPRS) in a sample of 474 patients with schizophrenia, replicated in an independent sample of 327 patients. The most commonly used 5-factor solution for the BPRS fit the data poorly. Exploratory factor analyses performed on the first sample led to the specification of a ...

Background: Electroconvulsive therapy (ECT) has been reported being a safe and effective treatment in schizophrenia. However, there are a limited number of studies assessing continuation ECT utilization in patients with schizophrenia giving partial response to pharmacological treatment. Objective: The aim of this study is to evaluate the effectiveness of continuation ECT in preventing relapse i...

Electroconvulsive therapy (ECT) is effective in treatment-resistant depression (TRD). It may act through intracellular process modulation, but its exact mechanism is still unknown. Animal research supports a neurotrophic effect for ECT. We aimed to investigate the association between changes in serum brain-derived neurotrophic factor (sBDNF) levels and clinical improvement following ECT in pati...