background: alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. in this study, we investigated the effect of sustained hypoxic ventilation o...

one of the more infrequent congenital diseases with a wide spectrum of symptoms and more complications of the right side of pulmonary artery (63% according to ten harkel) is unilateral pulmonary artery agenesis (upaa). the clinical presentation is variable, and many patients can be asymptomatic for many years and even throughout their lives. although the disease more frequently appears in child...

Background Pulmonary artery banding (PAB) is a technique of palliative surgical therapy used by congenital heart surgeons as a staged approach to operative correction of congenital heart defects. Materials and Methods We report 5- year experiences from January 2011 to January 2016 of Imam Reza Hospital center (a tertiary referral hospital in Mashhad city, North East of Iran) that consist of 50 ...

conclusions based on the results of this study, we suggest the use of a novel “time from the beginning of isovolumetric contraction to the peak of the s wave” (ttp) parameter in the tdi of the base of the rv free wall to predict ph with acceptable accuracy in comparison with rhc. results in our study, the ttp showed a significant inverse relationship with the pap. based on our results, a ttp of...

Unilateral Pulmonary Artery Agenesis (UPAA) is a rare congenital anomaly during the 4 th  week of gestational age. It is defined as an absence of pulmonary parenchyma and its supporting artery. A 9-year-old girl was admitted to our hospital because of chronic cough. Chest examination showed a decrement in lung sound of right hemi-thorax with expiratory wheeze. Chest radiography (CXR) revealed a...

Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the t...

we report two cases of tetralogy of fallot with pulmonary valve bacterial endocarditis where one extended to the branch of pulmonary artery (pa). this is a rare occurrence. aggressive supportive care plus early and radical surgery can be life saving.

coronary artery disease is one of the main causes of mortality in most developed countries. there is also an increasing rate of mortality in developing countries where in addition to coronary artery disease, infection diseases still not have been controlled. although, now a day coronary artery disease is responsible for half of deaths in developed countries, this regrettable event is increasing...

background pulmonary artery banding (pab) is a technique of palliative surgical therapy used by congenital heart surgeons as a staged approach to operative correction of congenital heart defects. materials and methods we report 5- year experiences from january 2011 to january 2016 of imam reza hospital center (a tertiary referral hospital in mashhad city, north east of iran) that consist of 50 ...