OBJECTIVES To see the early post-operative outcomes of off-pump versus on-pump coronary artery bypass graft surgery. METHODS This retrospective analytical study was conducted at Ch. Pervaiz Elahi Institute of Cardiology Multan, Pakistan. Our Primary outcome variables were; necessity of inotropic support, nonfatal myocardial infarction, ICU stay, nonfatal stroke, new renal failure requiring di...

Off-pump coronary artery bypass surgery reduces the myocardial injury associated with on pump surgery with cardiopulmonary bypass (CPB) and ischemic-cardioplegic arrest (CA). We sought to find a mechanistic explanation for this by comparing the transcriptomic changes in the myocardium of patients undergoing on- and off-pump surgery. Transcriptomic analyses were performed on left ventricular bio...

In this paper, the compact model of power efficiency for four-phase positive charge pump is derived. The model was verified by using post-layout simulation with 0.25μm triple-well flash memory technology. By including parasitic effects in the pump, the discrepancies between the model and the post-layout simulation results are within 4%.

Atrial fibrillation (AF) is the most common post-operative complication in patients undergoing coronary artery bypass grafting, with an increased incidence associated with advancing age. This study aims to determine whether off-pump coronary artery bypass (OPCAB) reduces the incidence of AF in a generalized population (mean age <70 years). A meta-analysis was performed including all randomised ...

BACKGROUND Due to advancement of non-surgical methods of coronary revascularization the patients referred for surgery have extensive and complex coronary anatomy. Patients with diffuse atheromatous coronary artery disease required coronary artery reconstruction or coronary endarterectomy (CE). Coronary endarterectomy on beating heart needs skill and better surgical technique. Coronary endartere...

a 47 year-old female died after mitral valve replacement. post-cardiopulmonary bypass right ventricle was not able to pump despite good left ventricular contractility. at microscopic examination, diffuse right ventricular fatty infiltration was found. we found no previous report of this pathology in patients with mitral stenosis

OBJECTIVE Cerebral injury, in both overt and subtle forms, is common following cardiac surgery. Current methods of assessment, most commonly neuropsychological testing, have several limitations and do not accurately define the anatomical and functional injury that occurs. We have assessed the degree of cerebral injury following on-pump and off-pump cardiac surgery using functional magnetic reso...

A 47 year-old female died after mitral valve replacement. Post-cardiopulmonary bypass right ventricle was not able to pump despite good left ventricular contractility. At microscopic examination, diffuse right ventricular fatty infiltration was found. We found no previous report of this pathology in patients with mitral stenosis

BACKGROUND Pump thrombosis in durable continuous-flow pumps is a barrier to long-term mechanical circulatory support. Earlier Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) data identified an increasing risk of pump thrombosis in recent years with the HeartMate II (HMII) left ventricular assist device. The current analysis examines pump thrombosis in the patient ...