Background: The idiopathic peptic ulcers (IPU), or non-Helicobacter pylori nonsteroidal anti-inflammatory drugs (NSAIDs)-associated ulcers, are a serious therapeutic challenge. prevalence of IPU is increasing in some parts the world. Objectives: This study aimed to determine southeastern Iran. Methods: In this cross-sectional study, total 367 patients with active ulcer were diagnosed by endosco...

Helicobacter pylori (H. pylori) infection is associated with several disorders of the gastrointestinal tract, including gastric cancer. Studies ours and others suggest that H. may affect melatonin synthesis in epithelial cells. On other hand, ameliorates as shown clinical trials experimental studies. Moreover, not only suppresses DNA-damaging reaction diet-related mutagens can initiate carcinog...

HIGHLIGHTS The interaction between innate and adaptive immune responses against H. pylori. virulence factors of pylori to evaluate the susceptibility infection. New treatment vaccination approaches for relating possible mechanisms. Mechanisms shaping considering genetics.

Helicobacter pylori (H. pylori) urease generates both ammonia (NH3) and carbon dioxide (CO2) from urea. NH3 helps H. to survive in the stomach part by neutralizing gastric acid. However, relationship between CO2 is not completed cleared. We examined effect of generated on multiplication using isogenic ureB mutant complemented strain JP26. Wild-type survived medium supplement with 1mM urea room ...

Objective(s): Treatment of Helicobacter pylori infection by common drugs may be associated with several problems such as antimicrobial resistance to commonly used antibiotics and side effects of employed drugs. Therefore, exploration of non-chemical compounds which are safer than chemical ones is becoming important as an alternative therapy. The purpose of this study w...

Background: Helicobacter pylori has caused gastritis leading to bleeding and iron deficiency anemia. H-pylori eradication results in better response oral treatment. Aim: To determine the frequency of improvement refractory anemia after successful H-pylori. Study design: Descriptive, case series. Methodology: Patients (n=89) anemia, 15-55 years either gender were included. After this taking rele...

Introduction: In addition to Helicobacter pylori, non-Helicobacter pylori helicobacters (NHPHs) have been diagnosed in the humans stomach that caused gastrointestinal diseases. This study aimed to evaluate the coinfection of H. pylori with NHPHs species in patients with gastric disorders in Iran.   Materials & Methods: This cross-sectional study was performed on 421 gastric biopsies form dysp...

Objective(s):Helicobacter pylori (H. pylori) is a pathogenic bacterium that colonizes the stomachs of approximately 50% of the world’s population. Resistance of H. pylori to antibiotics is considered as the main reason for the failure to eradicate this bacterium. The aim of this study was to determine the rate of resistant H. pylori strains to various antimicrobial agents in different areas of ...

H. pylori infection is usually acquired in early childhood. Its role in gastrointestinal and extra intestinal complaints and serious consequences in adulthood make it as challenging issues. Despite different clinical presentations, in most children, the presence of H. pylori infection does not lead to clinically apparent disease, even when it causes chronic active gastritis. Some of most import...

The antibacterial effect of the previously reported Bi2WO6/Ag3PO4/Ag Z-scheme heterojunction photocatalyst compared with a phytobiotics named, aqueous extract Persian Oak fruit. impact both materials on expression urease gene was checked in two kinds samples such as clinical and standard Helicobacter pylori (H. pylori). differences were collected by real-time PCR from strains H. well MIC MBC fo...