The bioavailability of the PAH (polycyclic aromatic hydrocarbon) model compound pyrene to the deposit-feeding polychaete Arenicola marina was studied at pyrene concentrations ranging from 0 to 10 ppm. By manipulating the sediment organic content, different distributions of pyrene between particle-associated pyrene, pyrene bound to dissolved organic matter (DOM) and freely dissolved pyrene were ...

Pluronic/bile salt/phospholipid mixed micelles (Pluronic/BS/PS-MM) drug carrier system for solubilization hydrophobic drugs was developed. A typical hydrophobic compound, pyrene, was selected as a representative hydrophobic compound to model the hydrophobic drugs. Five Pluronics, F68, F88, F98, F108, and F127 with different PPO chain length were studied. CMC data and solubilization capacities w...

In vivo and in vitro biotransformation of the polycyclic aromatic hydrocarbon (PAH) pyrene was investigated in the marine polychaete Nereis virens. Assays were designed to characterize phase I and II enzymes isolated from gut tissue. High-pressure liquid chromatography measurement of 1-hydroxypyrene, pyrene-1-glucuronide, pyrene-1-sulfate, and pyrene-1-glucoside appeared to be a sensitive metho...

background: asphalt workers are exposed to dangerous agents in his workplace that might result in occupational diseases. benzo (a) pyrene as a human carcinogen, is emission from hot asphalt and asphalt workers are exposed with it. the aim of this study was, evaluation of respiratory exposure to benzo (a) pyrene among asphalt workers. method: in this study, 42 samples were collected from breathi...

conclusions application of rhamnolipid biosurfactant produced by pseudomonas aeruginosa significantly improved pyrene removal in contaminated soils. results the pyrene removal efficiency in samples containing biosurfactant, without biosurfactant and controls, were 86.4%, 59.8% and 14%, respectively, after 63 days. the difference of pyrene removal efficiency between the biosurfactant-containing ...

polycyclic aromatic hydrocarbons (pahs) are a class of compounds consisting of more than twobenzene rings fused in a linear, angular, or clustered arrangement and do not contain hetero atomsor carry subsistent. pahs originate from various sources. they are primarily formed byincomplete combustion of carbon-containing fuels such as wood, coal, diesel, fat, or tobacco. thepresent study reports an...

Pyrene degradation is known in bacteria. In this study, Mycobacterium sp. strain KMS was used to study the metabolites produced during, and enzymes involved in, pyrene degradation. Several key metabolites, including pyrene-4,5-dione, cis-4,5-pyrene-dihydrodiol, phenanthrene-4,5-dicarboxylic acid, and 4-phenanthroic acid, were identified during pyrene degradation. Pyrene-4,5-dione, which accumul...

In this study, biotransformation products of pyrene were measured in the hepatopancreas of terrestrial isopods as biomarkers of polycyclic aromatic hydrocarbon (PAH) exposure. These products--pyrene-1-glucoside, pyrene-1-sulfate, an unknown pyrene conjugate, and 1-hydroxypyrene--were quantitated using high-performance liquid chromatography (HPLC) with fluorescence detection. In a controlled exp...