1 From the Julius Center for Health Sciences and Primary Care (E.B., P.J.N., T.B.v.d.W., Y.v.d.G.) and Depts of Radiology (W.P.T.M.M.), Neurology (L.J.K.), and Vascular Surgery (B.C.E.), Univ Medical Center Utrecht, Heidelberglaan 100, Rm D01.335, 3584 CX Utrecht, the Netherlands; Program for Assessment of Radiologic Technology, Dept of Epidemiology and Biostatistics, and Dept of Radiology, Era...

INTRODUCTION Patients who require prolonged mechanical ventilation (PMV) are increasing and producing financial burdens worldwide. This study determines the cost per QALY (quality-adjusted life year), out-of-pocket expenses, and lifetime costs for PMV patients stratified by underlying diseases and cognition levels. METHODS A nationwide sample of 50,481 patients with continual mechanical venti...

BACKGROUND We used a Monte Carlo computer simulation to estimate the effectiveness and cost-effectiveness of screening for acute hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-infected men who have sex with men. METHODS One-time screening for prevalent HCV infection was performed at the time of enrollment in care, followed by either symptom-based screening, screening ...

OBJECTIVE To investigate if published studies tend to report favourable cost effectiveness ratios (below 20,000 dollars, 50,000 dollars, and 100,000 dollars per quality adjusted life year (QALY) gained) and evaluate study characteristics associated with this phenomenon. DESIGN Systematic review. Studies reviewed 494 English language studies measuring health effects in QALYs published up to De...

Grauhan O, Huang Chang H, Albert W, Hiemann N, Meyer R, Lehmkuhl H, Dandel M, Knosalla C, Hübler M, Pasic M, Weng Y-C, Hetzer R (2010) Impact of Donor-transmitted Coronary Atherosclerosis on Quality of Life (QOL) and Quality-adjusted Life Years (QALY) after Heart Transplantation. Tx Med 22: 242-247 Impact of Donor-transmitted Coronary Atherosclerosis on Quality of Life (QOL) and Quality-adjuste...

Objective To evaluate the cost effectiveness of acupuncture in the management of chronic headache. Design Cost effectiveness analysis of a randomised controlled trial. Setting General practices in England and Wales. Participants 401 patients with chronic headache, predominantly migraine. Interventions Patients were randomly allocated to receive up to 12 acupuncture treatments over three months ...

Main Outcome Measures: Outcomes included life expectancy, quality-adjusted life expectancy, and lifetime costs. Cost-effectiveness ratios were in dollars per qualityadjusted life year ($/QALY) gained. Results: In the general population, screening 1 time, every 2 years, and annually saved 1.6, 4.4, and 5.2 QALYs per 1000 persons screened, with incremental costeffectiveness ratios of $10 100/QALY...