Objective(s): Alternative normalization methods were proposed to solve the biased information of SPM in the study of neurodegenerative disease. The objective of this study was to determine the most suitable count normalization method for SPM analysis of a neurodegenerative disease based on the results of different count normalization methods applied on a prepared digital phantom similar to one ...

A right heart catheterization with reversibility testing is recommended for the diagnosis and treatment of pulmonary arterial hypertension. In this 24 years-old woman, the inhalation of 5 microg iloprost transiently decreased mean pulmonary artery pressure from 62 to 36 mmHg and pulmonary vascular resistance from 11.0 to 4.9 Wood units, meeting the criteria of a "positive response". The echocar...

For the smooth normalization f : X → X of a singular variety X over a field k of characteristic zero, we show that for any conducting subscheme Y for the normalization, and for any i ∈ Z, the natural map Ki(X, X, nY ) → Ki(X, X, Y ) is zero for all sufficiently large n. As an application, we prove a formula for the Chow group of zero cycles on a quasi-projective variety X over k with Cohen-Maca...

MicroRNAs (miRNAs) are short, endogenous non-coding RNAs that function as guide molecules to regulate transcription of their target messenger RNAs. Several methods including low-density qPCR arrays are being increasingly used to profile the expression of these molecules in a variety of different biological conditions. Reliable analysis of expression profiles demands removal of technical variati...

in this paper we introduce the notions of uniformly quasi-primary ideals and uniformly classical quasi-primary submodules that generalize the concepts of uniformly primary ideals and uniformly classical primary submodules; respectively. several characterizations of classical quasi-primary and uniformly classical quasi-primary submodules are given. then we investigate for a ring $r$, when any fi...

Setting of this paper is Bishop's constructive mathematics. For a relation σ on a set with apartness is called quasi-antiorder if it is consistent and cotransitive. The quasi-antiorder σ is complete if holds . 0 1 / = σ σ − ∩ In this paper the following assertion ‘A quasi-antiorder is the intersection of a collection of quasi-antiorders.’ is given.

micrornas (mirnas) are short, endogenous non-coding rnas that function as guide molecules to regulate transcription of their target messenger rnas. several methods including low-density qpcr arrays are being increasingly used to profile the expression of these molecules in a variety of different biological conditions. reliable analysis of expression profiles demands removal of technical variati...

Using linear algebra methods we study certain algebraic properties of monomial rings and matroids. Let I be a monomial ideal in a polynomial ring over an arbitrary field. If the Rees cone of I is quasi-ideal, we express the normalization of the Rees algebra of I in terms of an Ehrhart ring. We introduce the basis Rees cone of a matroid (or a polymatroid) and study their facets. Some application...

We present a manually-adaptive extension of Quasi Monte Carlo (QMC) integration for approximating marginal densities, moments, and quantiles when the joint density is known up to a normalization constant. Randomization and a batch-wise approach involving (0; s)-sequences are the cornerstones of the technique. By incorporating a variety of graphical diagnostics the method allows the user to adap...