In the adult brain, the neural stem cell (NSC) pool comprises quiescent and activated populations with distinct roles. Transcriptomic analysis revealed that quiescent and activated NSCs exhibited differences in their protein homeostasis network. Whereas activated NSCs had active proteasomes, quiescent NSCs contained large lysosomes. Quiescent NSCs from young mice accumulated protein aggregates,...

Analysis of condition-specific behavior under stressful environmental conditions can provide insight into mechanisms causing different healthy and diseased cellular states. Functional networks (edges representing statistical dependencies) inferred from condition-specific expression data can provide fine-grained, network level information about conserved and specific behavior across different co...

A yeast culture grown in a nutrient-rich medium initially containing 2% glucose is not limited in calorie supply. When yeast cells cultured in this medium consume glucose, they undergo cell cycle arrest at a checkpoint in late G1 and differentiate into quiescent and non-quiescent cell populations. Studies of such differentiation have provided insights into mechanisms of yeast chronological agin...

Flotation process in mechanical cells is carried out in highly turbulent conditions. In this work, the impact of impeller speed on four characteristics of the quiescent zone, i.e. zone height, turbulence, solid percentage, and gas holdup, and their relationship with the entrainment is investigated, and it is shown why at a higher impeller speed, entrainment is not significant. The height of the...

Introduction Quiescent and dormant embryos, germination: definitions Nuclear characteristics of the cell population in quiescent embryos Distribution of quiescent embryo cell nuclei in different phases of the cell cycle How is the high G\ cell level of quiescent embryos established? What are the mechanisms controlling G\ cell accumulation? Controversial observations on the high G\ accumulation ...