This study was undertaken to determine if increasing maternal iodine intake through single dose tablets will decrease breast milk concentrations of the iodine-uptake inhibitor, perchlorate, through competitive inhibition. We also sought to determine if the timing of supplementation influences the fraction of iodine excreted in milk versus urine and to compare the effectiveness of iodized salt a...

It was in May, 1938 that Hertz et al. (1) published the first report on biological studies with a radioactive isotope of iodine. By today's standards these first studies were done under the least favorable conditions with an isotope whose half life of 25 minutes limited the studies that could be done. Notwithstanding the limitations put on these investigators they not only reaffirmed certain pr...

background: ionizing radiation irradiated from iodine-131 can induce dna damage and cell death. the cellular dna damage is the cause of mutation and cancer. the micronucleus assay in polychromatic erythrocytes was applied to assess the radio-protective effect of turmeric extract on genotoxic potential of iodine therapy. materials and methods: thirty six male albino rats were randomly divided in...

Iodine is an essential micronutrient especially important in the neurodevelopment of infants. Spot samples of urinary iodine (UI) are used as an epidemiologic index of adult iodine nutrition. Individual infant iodine nutrition is of vital importance, but infant urine is difficult to collect, much less a 24 h sample. Monitoring the intake provides a pragmatic solution for determining infant iodi...

Background: Ionizing radiation irradiated from iodine-131 can induce DNA damage and cell death. The cellular DNA damage is the cause of mutation and cancer. The micronucleus assay in polychromatic erythrocytes was applied to assess the radio-protective effect of Turmeric extract on genotoxic potential of iodine therapy. Materials and Methods: Thirty six male albino rats were randomly divided in...

A new ICP-MS method for the determination of iodine in food samples is presented. The method makes use of a new miniature cyclonic spray chamber and a concentric glass nebulizer that is designed for low sample uptakes and is operated in a self-aspirating mode. As a consequence the wash-out was accelerated over conventional systems. This configuration allows the direct determination of iodine in...

Iodine in the form of Lugol's iodine is commonly prescribed for the treatment of goitre. Eighteen patients, who had positive history of ingestion of iodine are described. Some of the patients had hyperthyroidism when seen while others had thyrotoxicosis like symptoms after taking iodine. Hyperthyroidism was confirmed clinically, radio-isotopically and by response to treatment. Iodine was incrim...

thyroid scintigraphy has been helpful in detecting and evaluation of thyroid nodules. sodium pertechnetate tc-99m is the most commonly used radionuclide for thyroid imaging because of its general availability, favorable dosimetric characteristics and low cost. but, there are reports of occasional disparity in isotope uptake in lesions compared with radioiodide. in order to determine percentage ...

The use of radioactive iodine as an indicator in thyroid physiology has been described by Hertz, Roberts and Evans (1) and by Hertz, Roberts, Means and Evans (2, 3). Hamilton and Soley (4) have published data obtained by the use of radioactive iodine on goiter patients of several types. We have administered radioactive iodine (mainly the 8-day isotope I's1), obtained by bombarding tellurium wit...

Introduction: Differentiated thyroid carcinoma (DTC) is associated with excellent prognosis and high survival rates. This study was conducted to evaluate the influence of baseline and treatment-related factors on the health related quality of life (QoL) in cured DTC. Methods:This study was an analytic cross-sectional study on radio-iodine (RAI) treated DT...