ESTIMATION of cardiac output by the indicator-dilution method has been described by Kinsman, Moore, and Hamilton1 utilizing dye; however, radioactive methods for determination of cardiac output owe their inception to Prinzmetal and co-workers,2 who recorded radioactivity as a function of time by means of a counter over the heart after an intravenous injection of radioactive Na24. Nylin and Cela...

Stable isotope labeling (SIL) still has not been used very much in pediatric and perinatal clinical pharmacology. However, this method has numerous advantages. It allows one to determine the concentration of drugs with great sensitivity, thereby allowing quantification in small amounts of biologic samples. It also allows quantification with great specificity, eliminating interference by drug me...

Breath tests are non-invasive, non-radioactive, safe, simple and effective tests able to determine significant metabolic alterations due to specific diseases or lack of specific enzymes. Carbon isotope (13)C, the stable-non radioactive isotope of carbon, is the most used substrate in breath testing, in which (13)C/(12)C ratio is measured and expressed as a delta value, a differences between rea...

BACKGROUND The aim of the current study was to develop a marking technique as an internal marker to mark post blood meal mosquitoes by using stable phosphate isotope (32)P and determine the optimal concentration of it. METHODS An isotonic physiological saline solution, containing different concentration of radioactive isotope (32)P-labeled disodium phosphate (Na2H(32)PO4) was injected into ra...

A comparison of the radioactivity of potassium from human and commercial sources indicates that the radioactive isotope K(40) is probably 1 or 2 per cent less abundant in human potassium.

The design of future radioactive ion beam (RIB) facilities requires the forecast of radio isotope inventory after irradiation. At CERN – ISOLDE, we developed a software that estimates the activity of irradiated materials as a function of time dedicated to radioactive waste management. This tool can also be used for licensing procedures, planning of irradiation experiments and the estimation of ...

Non-invasive in vivo molecular imaging using radionuclides is based on the Radiotracer Principle of G. von Hevesy and the magic bullet concept by Ehrlich (1990). Both principles require administration of a radioactive tracer (a molecule labelled with a radioactive isotope which when injected into a living object can be traced by external radiation detection devices) and require that the quantit...

The RISING (Rare ISotope INvestigations at GSI) project [1] combines the EUROBALL Cluster Ge-detectors [2] and the fragment separator FRS [3] for high-resolution γ-ray spectroscopy measurements after in-flight isotope separation. In a first campaign relativistic Coulomb excitation of radioactive projectiles and the spectroscopy of nuclei excited in secondary fragmentation reactions were examine...

The most common isotope, plutonium-239, is produced when the most common isotope of uranium, uranium-238, absorbs a neutron and then quickly decays to plutonium. It is this plutonium isotope that is most useful in making nuclear weapons, and it is produced in varying quantities in virtually all operating nuclear reactors. As fuel in a reactor is exposed to longer and longer periods of neutron i...