نتایج جستجو برای: radiochemotherapy
تعداد نتایج: 1049 فیلتر نتایج به سال:
methods study on 34 patients diagnosed with rectal adenocarcinoma referred to oncology clinic was conducted. the treatment plan included 4050 cgy radiotherapy and 5fu, xeloda chemotherapy. all patients were assessed with 1/5 t mri 6 to 8 weeks after treatment. t1 and t2 images with sagittal, cronal and axial planes with and without contrast agent were obtained and interpreted by two radiologist...
BACKGROUND The radiochemotherapy regimen concomitantly employing temozolomide (TMZ) chemotherapy and radiotherapy (RT) 4 weeks after surgery, followed by 6 cycles of TMZ is a common treatment for glioblastoma (GBM). However, its median overall survival (OS) is only 14.6 months. This study was to explore the effectiveness and safety of early TMZ chemotherapy between surgery and chemoradiotherapy...
background: considering the ease of administration of capecitabne instead of infusional 5fu for concurrent radiochemotherapy (rct) of rectal cancer, the use of capecitabine has increased significantly in our radiation oncology department in the past years. thus we decided to compare the safety and survival with these 2 drugs by a retrospective review. methods: files of all patients receiving r...
Combination cancer therapy (e.g., radiochemotherapy) is widely used to enhance the therapeutic effects and prevent recurrence of cancer. However, side monotherapy are also amplified when treating with combination therapy. A locally activated drug delivery strategy that can release payload in a tumor-selective manner greatly needed overcome Here, we explore potential combining boron neutron capt...
HYPOTHESIS Preoperative radiochemotherapy for advanced rectal cancer results in fewer lymph nodes detected in the tumor-bearing specimen. DESIGN Nonrandomized control trial with analysis of a prospective perioperative database. SETTING Department of Surgery of a large-volume university hospital. PATIENTS All patients who underwent conventional open surgery to cure rectal cancer between Ja...
AIMS AND BACKGROUND In late 2001 at our institution, we started offering induction radiochemotherapy as a treatment option for superior sulcus tumors. Our aim was to evaluate treatment choices and outcome in this patient group treated over the past 7 years at our institution. METHODS The records of 34 patients were retrospectively reviewed and 33 were assessable for the analysis. RESULTS Tw...
Background. The main attention regarding prognostic and predictive markers in NSCLC directs towards the EGFR-targeted pathway, where the most studied genetic alterations include EGFR mutations, EGFR copy number, and KRAS mutations. We wanted to explore the prognostic impact of mutated KRAS in the stage III setting treated with high-dose radiochemotherapy. Methods. Samples were obtained from pat...
BACKGROUND Neoadjuvant radiochemotherapy has proven superior to adjuvant treatment in reducing the rate of local recurrence without impairing cancer related survival or the incidence of distant metastases. The present study aimed at addressing the effects of an intensified protocol of neoadjuvant treatment on the development of postoperative complications. METHODS A total of 387 patients unde...
AIMS AND BACKGROUND Rectal cancer is a common disease of elderly people. However, patients over 70 years of age are often not included in clinical trials. There is a lack of data concerning the use of radiochemotherapy with capecitabine in elderly patients. The aim of this study was to retrospectively evaluate the impact of preoperative radiochemotherapy with capecitabine on downstaging and sph...
PURPOSE The previous individual patient data meta-analyses of chemotherapy in locally advanced non-small-cell lung cancer (NSCLC) showed that adding sequential or concomitant chemotherapy to radiotherapy improved survival. The NSCLC Collaborative Group performed a meta-analysis of randomized trials directly comparing concomitant versus sequential radiochemotherapy. METHODS Systematic searches...
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