Blood–Brain Barrier In article number 2100812 by Smriti Singh, Agnieszka Morgenroth, and co-workers, Matrix metalloprotease (MMP) sensitive nanogels are synthesized for effective delivery of a radiopharmaceutical ([125I]ITdU) across the blood-brain barrier (BBB). The show efficient transcytosis in vitro model BBB co-cultured with glioblastoma cells. Once transcytosed, degrade an up-regulated MM...

Introduction The forms of radiopharmaceutical drugs clinical trial protocols the researcher’s brochure for studies reports on results trials Conclusion

Scintigraphy of the parathyroid glands continues to be controversial from several standpoints, including radiopharmaceutical choice, imaging protocol, results, and utility in clinical situations. This article reviews: the anatomy, physiology and pathology of the parathyroid glands; mechanisms of radiopharmaceutical localization; commonly accepted imaging protocols; image results; and the approp...

INTRODUCTION Preoperative wire-guided localisation (WGL) of impalpable breast lesions is widely used but can be technically difficult. Risks include wire migration, inaccurate placement, and inadequate surgical margins. Research shows that radioguided occult lesion localisation (ROLL) is quicker, easier, and can improve surgical and cosmetic outcomes. An audited introduction of ROLL was conduct...

T he 11th International Conference of Radiopharmaceutical and Molecular Therapy (ICRT) was held in Kochi, Kerala, India, November 13–17, and was organized under the umbrella of the World Association of Radiopharmaceutical and Molecular Therapy (WARMTH) and in cooperation with the International Atomic Energy Agency. The meeting included presentations on various applications of radionuclides for ...

The renaissance of Ga radiopharmacy has led to great advances in automation technology. The availability of a highly efficient, reliable, long-lived Ge/Ga generator system along with a well-established coordination chemistry based on bifunctional chelating agents have been the bases of this development in Ga radiopharmacy. Syntheses of Ga peptides were originally performed by manual or semiauto...

intoduction: therapeutic radiopharmaceuticals are radiolabeled molecules to deliver sufficient doses of ionizing radiation to specific disease sites such as bone metastases, brain and liver tumors and bone marrows malignancies including multiple myeloma. among some therapeutic radiopharmaceuticals, 166ho-1,4,7,10 -tetraazacyclo dodecane-1,4,7,10 tetraethylene phosphonic acid (166ho-dotmp) is us...