BACKGROUND AND OBJECTIVE The impact of photodynamic therapy (PDT) on the endometrium following topical application of 5-aminolevulinic acid (ALA) was studied in a rat model. Study Design/ MATERIALS AND METHODS Fluorescence microscopy revealed peak ALA to protoporphyrin IX (Pp IX) conversion 3-6 hours after application. Significantly higher Pp IX levels were observed in the endometrial glands ...

Gerard G. Nahum, MD I this issue, Drs. Samuels and Awonuga1 examine a case of uterine rupture associated with a second-trimester pregnancy within a congenital rudimentary uterine horn after administration of misoprostol. It is important because it emphasizes 1) the increased dangers associated with pregnancies that reside within congenital rudimentary uterine horns, 2) the importance of identif...

Two experiments were undertaken to investigate the cause of the observed tendency of Mongolian gerbil dams to gestate more male than female fetuses in their right uterine horns and more female than male fetuses in their left uterine horns. It was found in Expt 1 that female gerbils that had both ovaries removed and portions of their right ovary placed in both ovarian capsules gestated significa...

AIM The aim of this study was to examine the protective effects of vitamin C (VC) and vitamin E (VE) against hysterosalpingography (HSG)-induced epithelial degeneration and proliferation in rat endometrium. MATERIALS AND METHODS A total of 28 female Wistar albino rats were randomized into four groups: G1 (n=7; abdomen was opened and closed), G2 (n=7; 0.1 mL Lipiodol [ethiodized oil] was admin...

Genito-urinary tract or systemic infections of the gram-negative bacteria in pregnant women, causes abortions, preterm labor, and several other perinatal complications. LPS is the most potent antigenic component of the gram-negative bacterial cell wall and is known to modulate the expression of various proinflammatory cytokines. Here we investigate the role of the soluble form of IL-1 i.e., IL-...

Pregnancy in sheep is associated with changes in numbers of specific T-lymphocyte populations in the uterine endometrium. These changes probably contribute to evasion by the conceptus of maternal immunological rejection and indicate a possible role for T cells in placental growth, parturition and post-parturient uterine defence against infection. The purpose of the present experiment was to eva...

Cytotoxic agents, cadmium, iodoacetate, thio-TEPA, podophyllin, colchicine, and alcohol, were instilled in one uterine horn of the rat to observe their subsequent eflect on fertility. Cadmium and iodoacetate interfere with implantation in both horns without altering ovulation for periods of 1 to 2 months. Thio-TEPA produces a unilateral efiect for periods of 2 months. With alcohol this unilater...

OBJECTIVE The mechanism of aglepristone action in the placentation time in the bitch remains unclear. The aim of this study was to describe the mechanism by which aglepristone influences ovaries and uterus and to measure the levels of steroid sex hormones in non-pregnant bitches. MATERIALS AND METHODS Fourteen bitches assigned to a study (n=9) and control (n=5) group were given aglepristone a...

The gestation period of rats is on average 21 to 23 days. Conceptus can be detected by ultrasonography after the 8‐9th days pregnancy. total number fetuses per pregnancy 1 20. In some cases, abortion occurs depending many etiological factors, and it most common complication subject present case report was surgical management spontaneous using inhalation anesthesia in a rat. material female albi...