The main physiologic function of adipokines on the energy metabolism and cardiovascular homeostasis, among others, are well known. In last years, our laboratory is providing increasing evidence about possible role as mediators vascular damage, by inducing different pro-inflammatory pro-senescent mechanisms. secretion like visfatin or dipeptidylpeptidase-4 (DPP4) adipose tissue, particularly vis...

Inter leukin 3 is a 2 6 2 8 kD glycoprotein produced by antigenand lectinstimulated T lymphocytes, and constitutively released in culture by the mouse tumor cell line WEHI-3 (i). Ik-3 was purif ied to homogenei ty f rom material obtained f rom WEHI-3 cells (2), and the gene encoding it was isolated (3, 4). rIL-3 and IL-3 purif ied to homogenei ty have been shown (5-7) to p romote growth of prec...

During the last decade, increasing evidence suggests a strong association between chronic inflammation and cancer development among different types of cancer. The dysregulation of pro-inflammatory cytokines or their receptors is a common feature observed in many cancers [1]. Cancer cells take advantage of cytokine or cytokine receptor overexpression to benefit their own growth or invasive capac...