Background: Many advances have been made in reproductive medicine yet the spontaneous loss of a pregnancy remains the most common complication of pregnancy. The aetiology of spontaneous recurrent pregnancy loss (RPL) is multifactorial. Y chromosome microdeletions are found in approximately 7% of men with low sperm counts and, compared to the general population, a higher frequency of spontaneous...

background: miscarriage is a common phenomenon complicating more than half of pregnancies. recurrent pregnancy loss (rpl) is defined as three or more pregnancies lost before the twentieth week of gestation. it is believed that abnormality in maternal immune reaction to fetus and sharing of hla antigens might be associated with rpl. objective: to investigate the effect of hla-drb1 sharing betwee...

Recurrent Pregnancy Loss (RPL) is a disease, defined by two or more failed pregnancies, affecting about 5% pregnant women. RPL can be classified into primary RPL and secondary RPL [2]. Primary RPL aborters are those who have lost all previous pregnancies and have no live birth. Secondary RPL aborters are those who have at least one successful pregnancy, irrespective of the number of pregnancy l...

Endocrine disorders play a major role in approximately 8% to 12% of recurrent pregnancy loss (RPL). Indeed, the local hormonal milieu is crucial in both embryo attachment and early pregnancy. Endocrine abnormalities, including thyroid disorders, luteal phase defects, polycystic ovary syndrome, hyperprolactinaemia and diabetes have to be evaluated in any case of RPL. Moreover, elevated androgen ...

recurrent pregnancy loss (rpl) is a multifactorial disorder that remains idiopathic in 50% of the cases. the aim of this study was to investigate the association between mthfd1 as well as enos polymorphisms with idiopathic rpl. in a case-control study, 100 women with idiopathic recurrent pregnancy loss (prl) and 50 controls referred to noor laboratory, khoozestan, iran, were evaluated. genotypi...

ENGLISH/ANGLAIS] Affiliations: 1 Human Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Manasagangothri, Mysore, Karnataka, INDIA 2 Mediwave IVF and Fertility Research Hospital, Mysore, Karnataka, INDIA * Email Address for Correspondence/ Adresse de courriel pour la correspondance: [email protected]. in Accepted/Accepté: August, 2011 Full Citation: Chaithra PT, Sr...

OBJECTIVE To define the different causes of recurrent pregnancy loss (RPL) among Omani women. METHODS This retrospective study included all women with RPL seen between June 2006 and March 2012 in the RPL outpatient clinic in Sultan Qaboos University hospital, Muscat, Oman. The data were collected from the Hospital Information System by screening the electronic records of these patients. The s...

BACKGROUND Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms (C677T, A1298C) of MTHFR gene are associated with decreased MTHFR activity. OBJECTIVES The aim of this study was to determine the association bet...