Colon cancer (CC) is accepted as the third type of that causes death in world. Oxidative stress and low glutathione peroxidase (GPx) activity can cause CC. This study aims to show whether GPx Oxidized (GSSG)/ reduced (GSH) levels, which are considered oxidative markers, effective etiopathogenesis Erythrocyte isolation was performed 3 ml blood sample taken from volunteers aged 18-75 years. Hemog...

Recently, decreased glutamate (Glu) and reduced glutathione (GSH) levels were reported in the quadriceps femoris of patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate whether Glu and GSH levels are also modified in the diaphragm of these patients. Nine male COPD patients (forced expiratory volume in one second (FEV1) range 28-68% of the p...

When drought occurs during the maize-filling period, probability of yield decline increases. Abscisic acid (ABA) plays a regulatory role in physiological and metabolic activities plant development. However, its effect on antioxidant system maize leaves grain-filling stage is unclear. Maize plants (Zhengdan958) were used as an experimental material, ABA was sprayed stage. The placed under condit...

Bangia fuscopurpurea is a widespread intertidal seaweed that commercially cultured in China. This frequently exposed to hyposalinity stress, but little known about the adaptation mechanisms. Ascorbate−glutathione (AsA−GSH) cycle plays important roles many organisms under variety of abiotic including hyposaline stress. In this study, we investigated response key metabolites and enzymes involved ...

Hepatic synthesis and plasma levels of glutathione are markedly decreased in chronic liver disease. Because glutathione turnover is highest in kidneys, we examined whether changes in kidney glutathione occur in chronic cholestasis and whether they are related to kidney dysfunction in liver disease. Kidney and plasma GSH and GSSG were measured 1) in bile duct-ligated (BDL) rats; 2) in healthy ra...

introduction: heavy metals are important occupational and environmental pollutants that cause damage to various organs. although there is no effective therapy for such a poisoning, metallothionein has been shown to play a key role in the detoxification of cadmium (cd). evidence in the literature suggests that superoxide dismutase, glutathione peroxidase, and catalase constitute important defens...

The relationship between reduced glutathione (GSH) level and glutathione S-transferase (GST) activity in erythrocytes was examined, using sheep erythrocytes, which have varying GSH concentrations, and dog erythrocytes with an inherited high concentration of GSH. There was a positive correlation (r = 0.529, p < 0.001) between the GSH level and GST activity in sheep erythrocytes. In dog erythrocy...

During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that an important ubiquitous antioxidant molecule produced in human organs. The intracellular content GSH regulates the detoxifying capacity cells, as well immune response. particularly liver, where it serves major non-prot...

BACKGROUND The glucose degradation products (GDP) presentin conventional peritoneal dialysis fluids (PDF) may exert adverse effects toward human peritoneal mesothelial cells (HPMC). Some GDP can be detoxified by the glyoxalase/ glutathione pathway. It has been shown that the addition of glyoxalase I (GLO-I) and reduced glutathione (GSH) to PDF effectively eliminates GDP. We have therefore exami...