This review discusses recent developments in the field of nanosized biomaterials and their use in tissue regeneration approaches. The aim is to provide an overview of the research focused on nanoparticle-based strategies to stimulate regeneration. In particular, nanoparticles improve the regenerative capabilities of biomaterials offering ways to control surface and mechanical properties. Moreov...

This review discusses recent developments in the field of nanosized biomaterials and their use in tissue regeneration approaches. The aim is to provide an overview of the research focused on nanoparticle-based strategies to stimulate regeneration. In particular, nanoparticles improve the regenerative capabilities of biomaterials offering ways to control surface and mechanical properties. Moreov...

Background: There is a worldwide effort to present novel approaches for the development of tolerance-induction treatments in regenerative medicine, after years of investigation in clinical transplantation. Particularly, novel approaches are based on controlling the immune response, including the application of biomaterials or imitation of antigen-specific peripheral tolerance in either solid-or...

results afscs have the potential to be used in tissue repair and regeneration of bladder and kidney injuries, for the treatment of congenital anomalies like tracheal anomalies and spina bifida therapy etc. however, like other treatment, afscs also have some limitations such as low rate of differentiation of transplanted afscs and immune rejection. conclusions afscs have great therapeutic potent...

Background: There is a worldwide effort to present novel approaches for the development of tolerance-induction treatments in regenerative medicine, after years of investigation in clinical transplantation. Particularly, novel approaches are based on controlling the immune response, including the application of biomaterials or imitation of antigen-specific peripheral tolerance in either solid-or...

The evidence linking aging and cancer is overwhelming. Findings emerging from the field of regenerative medicine reinforce the notion that aging and cancer are profoundly interrelated in their pathogenetic pathways. We discuss evidence to indicate that age-associated alterations in the tissue microenvironment contribute to the emergence of a neoplastic-prone tissue landscape, which is able to s...

The explosion of interest in induced pluripotent stem cells has been fueled by their potential as a limitless source of cells to repair damaged tissues in any number of diseases. However, generating cells is only a small part of the problem; ensuring that these cells integrate into their new environment and function appropriately is now a more pressing challenge. In this issue’s Select, we focu...

Regenerative medicine would be the most exciting area in the recent scientific topics. In the history of human gene therapy, the severe combined immunodeficiency caused by the absence of adenosine deaminase (SCID-ADA) was the first monogenic disorder for which gene therapy was developed in 1990. Over 30 patients have been treated worldwide using the current protocols, and recent trials provided...