objective(s): coronary artery disease (cad) is the leading cause of death in both male and female worldwide. the main cause of cad is the atherosclerosis of coronary arteries, which is, mostly caused by genetic alteration. 50% of such cases occur in mitotic cells where single-strand breaks occur spontaneously or due to ionizing radiation. x-ray repair cross-complementing protein 1 (xrcc1) as a ...

among the lesions induced by chemotherapeutic drugs, dna double-strand breaks (dsb) are considered the most serious ones that can result in cell death, if it is not properly repaired. homologous recombination (hr) pathway is the main system for dsb repair and xrcc3 has a key role in this pathway. protein activity can be affected by the xrcc3 polymorphism. thus, in this study, the association be...

traumatic peripheral nerve injuries are among most important cause of physical disability among young adults. most partial injuries and some complete injuries recover without operative intervention, with early return of function appearing to be the most significant prognostic factor in these cases. return of function over time depends to a great extent on the underlying neuropathologic conditio...

this article explores the forms of moral repair that the wrongdoer has to perform in an attempt to make amends for her past wrongdoing, with a focus on the issues of interpersonal moral repair; that is, what a wrongdoer can do to merit her victim‘s forgiveness and achieve reconciliation with her community. the article argues against the very general demands of atonement that amount to an obliga...

we report the cases of two patients diagnosed with morgagni hernia who presented with nonspecific abdominal symptoms. both underwent laparo­scopic surgery that used a dual-sided mesh, polyvinylidene fluoride (pvdf; dynamesh ipom®). the procedures were successful and both patients were discharged with no complications. there was no recurrence in 18 months of follow up. herein is the report of th...

o b je c t i v e : to explore the pros and cons of early versus delayed intervention when dealing with severe blunt liver injury with significant hemoperitoneum and hemodynamic instability. m e t h o d s : this retrospective cross-sectional study was performed at the nemazi hospital, shiraz, southern iran, level i trauma center affiliated with shiraz university of medical sciences. the study po...

the effect of steel plate thickness on the repair effectiveness of rc beam is presented in this paper. a total of four beams were tested, one beam repaired by cfrp with a thickness of 1.2 mm and used as a control beam, and three beams repaired by a steel plate. steel plates with a thickness of 2 mm, 3 mm, and 4 mm were used in repairing the beams. the maximum load-carrying capacity, deflection ...

abstract traumatic descending thoracic aorta pseudo aneurysms have been treated traditionally with open surgery in the past, which have had noticeable rates of mortality and morbidity. a safer method of treatment for this disease is made possible with recent progress in endovascular treatment techniques. in this article, we present three cases of traumatic descending thoracic aorta pseudo aneur...

background:  parts of the implants placed over the meniscus during meniscal repair can wear down the cartilage in the contact zones and cause chronic synovitis. placing horizontal sutures under the meniscus may overcome this potential hazard. the purpose of this prospective study was to evaluate the midterm results of arthroscopic meniscal repair using submeniscally placed out-in horizontal sut...