BACKGROUND Very few studies have been performed to evaluate the efficacy and safety of narrow-band ultraviolet B (NBUVB) therapy in Indian patients with vitiligo and are of small sample size. AIMS The purpose of this study is to know the efficacy and safety of NBUVB in 150 vitiligo patients of various age groups. METHODS One hundred fifty patients (69 males, 81 females), aged 3-70 years, wi...

Narrow-Band Ultraviolet B (NB-UVB) in combination with topical therapy is a widely used treatment for non-segmental vitiligo (NSV). The location of the lesions influence on potential repigmentation response after therapy. To date however, these differences therapeutic between specific anatomical areas body have not been fully characterized. This study aimed to evaluate clinical NB-UVB 19 differ...

Psoralen and ultraviolet light A (PUVA) was the mainstay of vitiligo treatment before the introduction of narrowband UVB(NB-UVB). Eighteen patients treated with NB-UVB in Hospital Kuala Lumpur were retrospectively analyzed. Eight patients had Fitzpatrick skin phototype III and 10 with phototype IV. The mean duration of disease was 7.3 +/- 5.4 years, and the mean body surface area affected was 1...

BACKGROUND Vitiligo is an acquired pigmentary cutaneous disease, characterised by the progressive loss of melanocytes, resulting in hypopigmented skin areas which progressively become amelanotic. Classically, vitiligo treatments are unsatisfactory and challenging. Despite the continuous introduction of new therapies, phototherapy is still the mainstay for vitiligo repigmentation. AIM The aim ...

CONTEXT AND OBJECTIVE Recent studies have indicated that vitiligo areas contain inactive or dormant melanocytes. Melanin synthesis is related to tyrosinase presence and indicative of active metabolic state. The aim of this study was to compare repigmentation, epidermal melanocyte distribution and tyrosinase mRNA detection through reverse transcriptase polymerase chain reaction, in tissue sample...

The aim of our study was to analyze the results obtained with the ReCell system for surgical treatment of stable vitiligo. At Department of Plastic and Reconstructive surgery, University of Tor Vergata in Rome, we treated 15 patients with stable vitiligo during a 2-year period. The stability of vitiligo lesions varied between 1 and 4 years. The mean stability was 2.25. The disease activity acco...

Vitiligo is a relatively common acquired skin disorder, characterized by the progressive loss of melanocytes, which results in white patches. Classically, vitiligo’s treatments have been considered unsatisfactory and challenging. Recent advances in the knowledge of vitiligo’s pathogenesis have contributed to find better therapeutic options, so that at present many patients find a solution for d...

BACKGROUND Low catalase levels and cellular vacuolation in the epidermis of patients with vitiligo support major oxidative stress in this compartment. There is now in vivo evidence for increased epidermal hydrogen peroxide (H(2)O(2)) accumulation in this patient group by utilizing noninvasive Fourier Transform Raman spectroscopy (FT Raman). Epidermal H(2)O(2) can be removed with a topical appli...

Vol. 29, No. 5, 2017 653 Received August 12, 2016, Revised September 17, 2016, Accepted for publication September 26, 2016 Corresponding author: Hai-Jin Park, Department of Dermatology, Ilsan Paik Hospital, College of Medicine, Inje University, 170 Juhwa-ro, Ilsanseo-gu, Goyang 10380, Korea. Tel: 82-31-910-7224, Fax: 82-31-910-7227, E-mail: [email protected] This is an Open Access article dist...