Heavy exercise is associated with an increased risk of upper respiratory tract infections. Strenuous exercise also causes gastrointestinal (GI) symptoms. In previous studies probiotics have reduced respiratory tract infections and GI symptoms in general populations including children, adults, and the elderly. These questions have not been studied in athletes before. The purpose of this study wa...

Background & objectives: Coronaviruses are a large group of viruses and constitute a subfamily of Coronaviridae ranging from the common cold virus to viruses causing more acute diseases such as SARS (Severe Acute Respiratory Symptom), MERSE (Middle East Respiratory Symptom) and COVID-19 inflicting human respiratory system. The aim of this study was to evaluate the trend of changes in the clinic...

Nine patients with adult onset acid maltase deficiency were seen at the Nijmegen University Hospital and the St Elisabeth Hospital, Tilburg , during the period 1970-1982. Five of these patients developed respiratory failure, and in four this was the initial symptom. The occurrence of respiratory failure as an early symptom of this muscular disease is discussed.

RATIONALE Common colds are associated with acute respiratory symptom exacerbations in COPD patients. OBJECTIVE To determine exacerbation risk and severity in COPD patients with/without coincident self-reported colds. METHODS Global initiative for chronic Obstructive Lung Disease stage I-IV COPD patients electronically transmitted respiratory symptom diaries to research staff daily between D...

A diary study on a random sample of 625 Swiss children aged 0 to 5 yr was conducted in two cities in Switzerland to investigate the association between air pollution and respiratory symptoms. Total suspended particulates (TSP), SO2 and NO2 were measured by city monitor. In addition, passive samplers inside and outside the home measured NO2 concentration during the 6 wk each child was on the dia...

BACKGROUND Children with severe neurodisability (ND) commonly suffer from chronic respiratory symptoms that impact greatly on quality of life, and lead to recurrent hospital admissions. This morbidity (and its causes) is poorly described, despite being well recognised by paediatricians. In this study, we characterised respiratory symptoms in children with ND at times of stability and deteriorat...

INTRODUCTION Gastro-oesophageal reflux disease (GORD) is the pathological reflux of gastric contents into the oesophagus. The oesophagus and the upper respiratory tract have a common origin from the foregut. There is increasing evidence for multiple associations of GORD with the upper respiratory tract. OBJECTIVES To study the presence of and association of upper respiratory symptoms (URS) wi...