Several clinical observations suggest that pregnancy alters reticuloendothelial (RES) function. Pregnant women are more susceptible to paralytic poliomyelitis'," and influenza,' and there is a direct relationship of multiparity to bacteruria.' Pregnancy also appears to be the state most likely to prepare a human being for a generalized Shwartzman reaction. Measurements of RES function in pregna...

The processing of erythrocyte iron by the reticuloendothelial cell has been characterized by kinetic measurements of blood radioactivity made after the intravenous injection of heat-damaged erythrocytes labeled with (59)Fe and of transferrin-bound (55)Fe. The early reticuloendothelial release of iron, a matter of hours, was calculated from the plasma turnover rate of (55)Fe and the plasma reapp...

Cytarabine is the drug of choice for treatment of leukemia. However, many formulations have been prepared, due to certain limitations they could not prove to be effective ones, therefore magnetic microspheres are formulated as they minimize the Reticuloendothelial clearance and target site specificity can be increased. The current study aimed to utilize nanotechnology to develop magnetic micros...