introduction: n-methyl-d-aspartate receptor subunits antibody (nr2-ab) is a sensitive marker of ischemic brain damage in clinical circumstances, such as cerebrovascular accidents. we aimed to assess the value of serum nr2-ab in predicting the post-cardiopulmonary resuscitation (cpr) survival. methods: in this cohort study, we examined serum nr2-ab levels 1 hour after the return of spontaneous c...

BACKGROUND Prediction of the return of spontaneous circulation (ROSC) in cardiac arrest patients is a parameter for deciding when to stop cardiopulmonary resuscitation (CPR) or to start extracorporeal CPR. We investigated the change in transcutaneous PCO2 (PtcCO2) in cardiac arrest patients. METHODS This study was carried out as a retrospective chart review. Patients with out-of-hospital card...

Introduction Trans-nasal cooling started during cardiopulmonary resuscitation (CPR) has shown to improve the return to spontaneous circulation (ROSC) and survival rate in an experimental prolonged cardiac arrest model. A multicenter randomized trial (PRINCE) has also suggested an improved neurological outcome in patients receiving trans-nasal cooling during CPR in the prehospital setting when c...

AIM Survival rates after out-of-hospital-cardiac-arrest (OHCA) differ widely between EMS systems. Since hypertonic saline appears to improve long-term outcome after OHCA, some local EMS systems have included it in their treatment protocols for OHCA. Our first aim was to give a quality review of one of these protocols. Our second aim was to assess whether short-term survival improves when hypert...

Researchers in South Korea previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest. In a new study, the same team of researchers compared the efficacy of brain computed tomography (CT) and DW-MRI to predict neurologi...

Researchers in South Korea previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest. In a new study, the same team of researchers compared the efficacy of brain computed tomography (CT) and DW-MRI to predict neurologi...

Researchers in South Korea previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest. In a new study, the same team of researchers compared the efficacy of brain computed tomography (CT) and DW-MRI to predict neurologi...

Monitoring Immediately Before, During, and After Arrest Assessment During CPR At present there are no reliable clinical criteria that clinicians can use to assess the efficacy of CPR. Although end-tidal CO2 serves as an indicator of cardiac output produced by chest compressions and may indicate return of spontaneous circulation (ROSC),1,2 there is little other technology available to provide re...

Researchers in South Korea previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest. In a new study, the same team of researchers compared the efficacy of brain computed tomography (CT) and DW-MRI to predict neurologi...

Only one in ten patients survives cardiac arrest (CA), underscoring the need to improve CA management. Isoflurane has shown cardio- and neuroprotective effects in animal models of ischemia-reperfusion injury. Therefore, the beneficial effect of isoflurane should be tested in an experimental CA model. We hypothesize that isoflurane anesthesia improves short-term outcome following resuscitation f...