Hereditary hypophosphatemic rickets (HHR) are a group of diseases characterized by renal phosphate wasting causing growth retardation, rickets and osteomalacia. The most common form is the X-linked dominant hypophosphatemic rickets caused by inactivating mutations in the PHEX gene. The other hereditary hypophosphatemic syndromes present a lower prevalence. These include autosomal dominant hypop...

OBJECTIVE To estimate the incidence of nutritional rickets and the incidence and prevalence of hereditary rickets. DESIGN Population-based retrospective cohort study based on a review of medical records. METHODS Patients aged 0-14.9 years referred to or discharged from hospitals in southern Denmark from 1985 to 2005 with a diagnosis of rickets were identified by register search, and their m...

The aim of this study is to confirm our original hypothesis that maternal deficiency of vitamin D is a major factor in development of rickets in her breastfeeding infant and review the literature. In six months from October 2008 to March 2009 out of 136 infants with diagnosis of clinical rickets, seen in Medinah Maternty and Chlidrens Hospital, 40 infants and their mothers were included in this...

Risk factors for rickets of prematurity have not been re-examined since introduction of high mineral formula, particularly in ELBW infants. We analyzed the incidence and the risk factors of rickets in extremely low birth weight (ELBW) infants. As a retrospective case-control study from 2004 to 2008, risk factors were analyzed in 24 patients with rickets versus 31 patients without. The frequency...

Rickets, a disease of vitamin D deficiency, is rarely confronted by the practicing pediatrician in the United States today. At the turn of the 20th century, rickets was rampant among the poor children living in the industrialized and polluted northern cities of the United States. With the discovery of vitamin D and the delineation of the anti-rachitic properties of cod-liver oil by the 1930s, i...

Vitamin D deficiency rickets presenting with hypocalcemia and clinical rickets is not uncommon in sunny countries as it is supposed to be [1]. Factors associated with the increased prevalence of nutritional rickets in sunny countries, included housing, environmental factors and customs associated with avoidance of sun by every member of the families, especially mothers who were found to be vita...

This descriptive cross-sectional community-based study was carried out in Ile-Ife, Nigeria to assess the knowledge of mother's on the aetiology of rickets associated knee deformities and the cultural perception of its treatment. Data collection was done using interviewer based semi structured questionnaires. A total of 464 questionnaires were administered with a response rate of 86.9%. Over hal...

Twenty nine patients with rickets were studied in a one year period. The majority of patients (17/29) were below 2 years of age. Most of them had nutritional rickets resulting from a combination of factors. Premature delivery, nonexposure to sunlight, nutritional marasmus and inappropriate dietary intake. Some had familial hypophosphataemic rickets, others had renal tubular acidosis while the r...

the purpose of this study was to determine the incidence of rickets types in broiler chickens on the basis of gross and microscopic lesions in field clinical cases with regard to differential pathomorphological diagnosis.clinical, serological, gross anatomy and histological investigations were carried out in broiler chickens with signs of rickets. the survey included 12 finisher broiler flocks ...

Reports of vitamin D-deficiency rickets and its associated morbidity continue among inadequately supplemented, dark-skinned breastfed infants. Despite the new vitamin D dietary guidelines, there remain significant numbers of unsupplemented breastfed infants. Here we report a case of subclinical vitamin D-deficiency rickets. This patient had biochemical and radiographic but not clinical evidence...