For the design of steel-lined pressure tunnels and shafts in anisotropic rock, it is common practice to assume for the computation that the system stands in isotropic medium with the lowest stiffness measured in situ. In this paper, stresses and displacements in the steel liner of a particular steel-lined pressure tunnel are numerically assessed taking into account the anisotropic behavior of t...

wall displacements and ground pressure acting on the lining of a tunnel increase with time. these time-dependent deformations are both due to face advance effect and to the time-dependent behavior of the rock mass.  viscoelastic materials exhibit both viscous and elastic behaviors. thorough this study, the effect of different linear viscoelastic models including maxwell, kelvin and kelvin-voigt...

The physical properties of the extracellular matrix (ECM), such as stiffness, are involved in the determination of the characteristics of cancer cells, including chemotherapy sensitivity. Resistance to chemotherapy is often linked to dysfunction of tumor suppressor p53; however, it remains elusive whether the ECM microenvironment interferes with p53 activation in cancer cells. Here, we show tha...

Wall displacements and ground pressure acting on the lining of a tunnel increase with time. These time-dependent deformations are both due to face advance effect and to the time-dependent behavior of the rock mass.  Viscoelastic materials exhibit both viscous and elastic behaviors. Thorough this study, the effect of different linear viscoelastic models including Maxwell, Kelvin and Kelvin-Voigt...

We propose a new method for measuring velocities and polarizations of the compressional and shear waves. The method consists of measuring time dependent displacement of a particular point on the sample surface in three independent directions by a laser Doppler interferometer. The high accuracy of these measurements makes the determination of the polarization straightforward, and thus the identi...

1.INTRODUCTION Some forty years ago, most opening supports and reinforcements were designed using empirical rules defining ground loads acting on the supporting structures. This approach is still popular and interest in it has been renewed by the use of rock mass classification systems (Barton et al. 1974, Bieniawski, 1974,1976,1989). Correlations between rock mass conditions and the type of su...

Electrospinning is a simple and efficient method of fabricating a non-woven polymeric nanofiber matrix. However, using fluorinated alcohols as a solvent for the electrospinning of proteins often results in protein denaturation. TEM and circular dichroism analysis indicated a massive loss of triple-helical collagen from an electrospun collagen (EC) matrix, and the random coils were similar to th...

This paper is an overview of quasistatic measurement technique used to determine mechanical properties of sound absorbing materials. Experimental context and behaviour of polymer foam and rock wool are summarized. Concerning parameters are: static and dynamic strains, dynamic effects such as skeleton resonance and coupling with saturating fluid. Material anisotropy and frequency dependance of c...

Tumors are stiffer than normal tissue, and tumors have altered integrins. Because integrins are mechanotransducers that regulate cell fate, we asked whether tissue stiffness could promote malignant behavior by modulating integrins. We found that tumors are rigid because they have a stiff stroma and elevated Rho-dependent cytoskeletal tension that drives focal adhesions, disrupts adherens juncti...