In this article, the second part of a two-part series on rosacea, emphasis will be placed on persistent facial erythema. Despite variations in the intensity of visible redness, persistent facial erythema is a very common and consistent finding among patients with rosacea, including those with presentations classically defined as papulopustular rosacea, erythematotelangiectatic rosacea, and in m...

Purpose To discuss two rare presentations of ocular rosacea in a Hispanic patient and an African American patient with unusual ocular manifestations. Case Report Case  1: a 43-year-old Hispanic woman presented with right eye corneal perforation. Her prior medical history was significant for rosacea only, diagnosed clinically by a dermatologist. Her eye exam showed signs of bilateral ocular ro...

Background. Rosacea is a chronic skin disease, possibly following the neurogenic skin inflammation model. Neurokinin B, involved in the pathogenesis of Parkinson's disease, frequently coexisting with subsequent onset of rosacea, is an endogenous ligand of the tachykinin receptor 3 (TACR3). Methods. 128 rosacea patients and 121 matched controls were genotyped for rs3733631 by PCR-RFLP and analyz...

Rosacea is a common chronic, and sometimes progressive, dermatosis. It is characterized, alone or in combination, by central facial erythema,symmetric flushing, stinging sensation, inflammatory lesions (papules and pustules), telangiectasias, and phymatous changes (tissue hyperplasia and nodules). Rosacea can occur in adults of any ethnicity,and adversely affects patients' quality of life. The ...

Heat, sun exposure, environmental factors and specific foods can trigger flares in rosacea. The exact etiology of rosacea remains unknown, but is likely multifactorial. Infectious agents, such as Demodex, have been hypothesized as causative agents. In one recent study, staphylococcus epidermidis was felt to play a role in pustular and ocular rosacea. Vascular instability and pilosebaceous unit ...

Rhinophyma is the most prevalent presentation of the phymatous subtype of rosacea. Rosacea subtypes include erythematotelangiectatic type (type 1), papulopustular rosacea (type 2), phymatous rosacea (type 3) and ocular rosacea (type 4).[1] Phymatous rosacea is characterized early by prominent follicular pores or patulous follicles with mild swelling while advanced disease reveals pronounced hyp...

A Medline search of the world literature turned up over 600 papers published in the last ten years in which the term rosacea appeared in the title. National and international dermatologic meetings have prominently featured symposia on acne vulgaris for more than four decades. It is only in the last decade that rosacea has begun to receive comparable attention on the educational programs. Rosace...

OBJECTIVE To evaluate the clearing and intensity of symptoms of rosacea 60 days after the treatment of Helicobacter pylori infection. DESIGN Randomized, double-blind, placebo-controlled clinical trial. SETTING The dermatology section of a large multispecialty clinic in the North Central United States. PARTICIPANTS Men and women older than 25 years with active signs of rosacea who tested p...

BACKGROUND Rosacea is a common inflammatory facial skin condition. Recent genetic and epidemiological studies have suggested pathogenic links between rosacea and gastrointestinal disorders, but data are limited. OBJECTIVES The objective was to investigate the association between rosacea and coeliac disease (CeD), Crohn disease (CD), ulcerative colitis (UC), Helicobacter pylori infection (HPI)...

Rosacea is a common dermatological condition that predominantly affects the central regions of the face. Rosacea affects up to 3 % of the world's population and a number of subtypes are recognized. Rosacea can be treated with a variety of antibiotics (e.g. tetracycline or metronidazole) yet no role for bacteria or microbes in its aetiology has been conclusively established. The density of Demod...