conclusions this report aimed to increase awareness of the occurrence of extra-intestinal systemic manifestations of rotavirus infection. although such cases may be rare, they still suggest that that rotavirus is a systemic viral infection. case presentations we report three pediatric cases of rotavirus infection: one accompanied by encephalopathy and two with elevated hepatic transaminase acti...

objective: group a rotaviruses (garv) are responsible for the vast majority of severe diarrhea worldwide that kills an estimated 600,000-870,000 children annually. since infantile gastroenteritis is a main health problem, therefore diagnosis and treatment of this disease is crucial. gene rearrangements have been detected in vitro during serial passages of the virus at a high multiplicity of inf...

rotavirus is a common infection causing 450,000 deaths annually primarily in children 5 years and below. despite the high burden of disease, little is known about the epidemiology of rotavirus in libya. the aim of this study was to estimate the rotavirus disease burden among libyan children.a cross-sectional study was carried out prospectively among children 5 years old and below between august...

background and aims: one of the major causes of acute diarrhea in children during the cold season in iran is infection by rotavirus. children infected with rotavirus often require hospitalization. several studies on human and animals have shown that enterotoxigenic escherichia.coli and rotavirus are the most common coinfection causing diarrhea. there are other reports indicating occurrence of r...

Rotaviruses are the most common cause of severe diarrhea in children under 5 years of age worldwide with a higher prevalence in developing countries. In accordance with the World Health Organization (WHO) recommendations for the global use of rotavirus vaccines, it is important to review trends of rotavirus epidemiology, distribution and diversity of rotavirus strains in the pre-vaccine period....

background and aims: in humans the group a rotaviruses are associated with endemic diarrhea in children under the age of 5, leading to approximately 800,000 deaths every year. introduction of rotavirus vaccines into childhood immunization programs can contribute to substantial reduction in mortality from rotavirus gastroenteritis in developing countries and virtually eliminating hospitalization...

rotavirus infections are one of the etiological agents of infantile and children,s gastroenteritis.in this study 450 fecal samples from children under 2 years old from cities of Tehran nad Zahedan were collected.of these specimens.73 samples which were cosidered as moderately positive(++) by ELISA were selected.SDS-PAGE analysis showed fifty six different rotavirus electrophoretypes from which ...

Background: VP4 protein is as spikes on rotavirus outer capsid shell which is responsible for virus attachment to the host. VP4 induces production of neutralizing antibodies which could be used for serotyping of different isolates. Methods: Simian rotavirus SA11 gene 4 cDNA was cloned into a cloning plasmid pDONRTM by recombination reaction using clonase II enzyme mix. The resulting clone was c...

rotavirus is the most important pathogen responsible for acute diarrhea in infants and young children. the incidence of rotavirus infection was studied in 156 children less than six years of age who were suffering from acute gastroenteritis, between february 22, 2006 and february 21, 2007 in mashhad. rotavirus antigen was detected by latex agglutination test (rotascreen) in 28.8% of the stool s...