Force probe techniques such as atomic force microscopy can directly measure the force required to rupture single biological ligand receptor bonds. Such forces are related to the energy landscape of these weak, noncovalent biological interactions. We report unbinding force measurements between complementary strands of DNA as a function of temperature. Our measurements emphasize the entropic cont...

In this research, two new methods that improve the drawing depth of deep-drawing processes have been introduced. In the first technique, by creating ridges on the punch surface, the stress concentration is decreased on the blank near the punch edge, in turn increasing the drawing depth. The second method is based on the principle of reducing resistant force in the flange area between the die, t...

Curvatures in the most probable rupture force (f*) versus log-loading rate (log r(f)) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimensional free energy profile with multiple barriers or a single barrier with force-dependent transition state. Here, we provide a criterion to select one scenario over another. If the rupture dynamics occurs b...

Increasing the mechanical stability of artificial polymer materials is an important task in materials science, and for this a profound knowledge of the critical mechanoelastic properties of its constituents is vital. Here, we use AFM-based single-molecule force spectroscopy measurements to characterize the rupture of a single silicon-oxygen bond in the backbone of polydimethylsiloxane as well a...

agricultural products are affected by static and dynamic forces at different stages of harvesting, handling and processing. in most cases, the damages are inflicted upon raw products. in the present study the mechanical properties of tomato fruits were found out for two cultivars (super bta and petoerly ch), during 4 periods of time (1, 5, 10 and 15 days past harvest), and at two levels of frui...

Single-molecule mechanical manipulation has enabled the quantitative understanding of the kinetics of bond ruptures as well as protein unfolding mechanism. Single-molecule experiments with theoretical models have allowed one to gain insight into free energy landscape for chemical bond and/or protein folding. For mechanically induced bond rupture, the bond-rupture kinetics may be governed by loa...