Background: Right ventricular outflow tract ventricular tachycardia (VT) and ventricular premature complexes (VPCs) are characterized as benign in entity with ECG morphology showing LBBB pattern and inferior axis. Pathogenic mechanisms in the genesis of RVOT VT/VPC remain largely unknown. We aimed to investigate the neural mechanism in RVOT VT/VPC in canine model. Methods: Twelve mongrel dogs (...

Ventricular arrhythmias commonly originate from the right ventricular out-flow tract (RVOT). However, the electrophysiological characteristics and Ca(2+) homoeostasis of RVOT cardiomyocytes remain unclear. Whole-cell patch clamp and indo-1 fluorometric ratio techniques were used to investigate action potentials, Ca(2+) homoeostasis and ionic currents in isolated cardiomyocytes from the rabbit R...

OBJECTIVES We examined the relationship among biventricular hemodynamics, pulmonary regurgitant fraction (PRF), right ventricular outflow tract (RVOT) aneurysm or akinesia, and baseline and surgical characteristics in adults with repaired tetralogy of Fallot (rTOF). BACKGROUND The precise relationship of pulmonary regurgitation with biventricular hemodynamics has been hampered by limitations of...

BACKGROUND Idiopathic ventricular arrhythmias of left bundle branch block inferior axis morphology are usually localized to the right ventricular outflow tract (RVOT), presumably below the pulmonic valve (PV). However, the PV location is usually not confirmed by direct visualization. METHODS AND RESULTS Intracardiac echocardiography was used to visualize and tag the PV annulus, which was then...

BACKGROUND#ENTITYSTARTX02014;: Electrical heterogeneity of the right ventricular outflow tract (RVOT) is regarded as one of the main electrophysiological substrates for Brugada syndrome. Recently quinidine has shown efficacy in patients with Brugada syndrome due to its ability to inhibit potassium current especially 4-aminopyridine-sensitive, non-Ca(2+) -dependent transient outward potassium cu...

We present three cases of active fixation pacemaker lead implantation, where the leads were believed to be inserted in the right ventricular outflow tract (RVOT) septal position, using established radiological criteria. However, when the exact location of the leads was documented by three-dimensional echocardiography, true septal RVOT position was achieved in only one patient. In the other two ...

BACKGROUND Pacing from the right ventricular apex is associated with long-term adverse effects on left ventricular function. This has fuelled interest in alternative pacing sites, especially the septal aspect of the right ventricular outflow tract (RVOT). However, it is a common perception that septal RVOT pacing is difficult to achieve. METHODS AND RESULTS In this article, we will review the...

OBJECTIVES False aneurysm of the right ventricular outflow tract (RVOT) is one of complications after surgery of congenital heart disease. It is controversial about materials for reconstruction of RVOT in this setting, when associated with pulmonary hypertension or bacterial infection. Pulmonary homograft seems to be the first choice, but its availability is extremely limited in Japan. METHOD...

AIMS Radiofrequency catheter ablation is considered first line treatment for symptomatic patients with right ventricular outflow tract tachycardia (RVOT). The role of ablation in arrhythmogenic right ventricular dysplasia (ARVD) is more limited. As such, differentiating between the two conditions is essential. METHODS AND RESULTS This study compared non-invasive findings, magnetic resonance i...