OBJECTIVE To characterize the physiologic nature of the vestibular dysfunction that occurs with the normative aging process. STUDY DESIGN Cross-sectional study. SETTING Tertiary care academic medical center. PATIENTS Fifty individuals age 70 years and above. INTERVENTIONS Head thrust dynamic visual acuity testing and cervical and ocular vestibular-evoked myogenic potential (VEMP) testin...

One of the primary challenges that sensory systems face is extracting relevant information from background noise. In the auditory system, the ear receives efferent feedback, which may help it extract signals from noise. Here we directly test the hypothesis that efferent activity increases the signal-to-noise ratio (SNR) of the ear, using the relatively simple teleost ear. Tone-evoked saccular p...

meniere’s disease is the disorder of inner ear characterized by vertigo, tinnitus and sensorineural hearing loss. the vestibular evoked myogenic potential (vemp) test could be useful in the analysis of saccular function, and diagnosis of meniere’s disease. in this study, we’ve analyzed the saccular function, using vemp test in different groups of meniere’s disease. patients were categorized as ...

Saccular cysts in infants are rare lesions of the larynx and may result in respiratory obstruction and severe dyspnea. Herein we present a case of saccular cyst in a three-month-old infant. She was presented with severe stridor and respiratory distress. She had been followed with the diagnosis of tracheomalacia for three months elsewhere. Direct laryngoscopy of the larynx revealed a saccular cy...

BACKGROUND AND PURPOSE Saccular intracranial aneurysm is a common disease that may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall inflammation have been associated with saccular intracranial aneurysm rupture. We investigated how saccular intracranial aneurysm hemodynamics is associated with wall remodeling and inflammation of the saccular intracranial aneurys...

OBJECTIVES/HYPOTHESIS To review a large cohort of adult saccular cyst patients and update current management of saccular cysts. STUDY DESIGN Retrospective review of treatment of adult patients with saccular cysts. METHODS Medical records were reviewed of all adult patients with saccular cysts identified between July 1, 2005 and August 31, 2009 at a tertiary care voice center. RESULTS Sixt...

Connections from saccular afferents to vestibular neurons were studied by means of intracellular recordings of excitatory (E) and inhibitory (I) postsynaptic potentials (PSPs) in vestibular neurons after focal stimulation of the saccular macula in decerebrated cats. Focal stimulation was given to the saccular macula in two ways, in which the polarity of stimulus current via a pair of electrodes...

The majority of MCA aneurysms are saccular lesions that arise at the MCA bifurcation region [1-5]. Aneurysms involving the M1 segment are less common, accounting for approximately12% of MCA aneurysms, and are generally small saccular lesions at the origin of the anterior temporal artery or a lenticulostriatal perforator [6,7]. MCA-M1 fusiform lesions vary significantly from their saccular count...

In goldfish and other otophysans, the Weberian ossicles mechanically link the saccule of the inner ear to the anterior swimbladder chamber (ASB). These structures are correlated with enhanced sound-pressure sensitivity and greater sensitivity at high frequencies (600-2000 Hz). However, surprisingly little is known about the potential impact of the ASB on other otolithic organs and about how aud...