OBJECTIVES Ischemia/reperfusion (I/R) injury of spinal cord is leading to the paraplegia observed. In this study, we investigated the protective effect of the saffron extract on spinal cord I/R injury. MATERIALS AND METHODS Thirty five male Sprague-Dawley rats were divided into 5 groups: intact, sham surgery, normal saline (NS), low dose saffron aqua extract, high dose saffron aqua extract. ...

More and more saffron has been cultivated in China because of the increasing saffron demand, but no paper has studied the influence of drying methods on the quality of Chinese saffron. In this paper, three different dehydration treatments applied in actual production were evaluated: dehydration with electric oven, vacuum oven, and microwave. We determined that the highest quality of saffron wil...

BACKGROUND Crocus sativus, known as saffron crocus, is best known for the spice saffron. Saffron use spans more than 3500 years, however, its toxicity on neonates during lactation has not yet evaluated. OBJECTIVES This study was aimed to examine the acute toxicity of saffron on adult mice and its nephrotoxicity and hepatotoxicity on neonates of lactating mothers that used saffron during lacta...

We recently identified saffron cod Eleginus gracilis as a dominant fish species in nearshore habitats (<5 m deep, <20 m offshore) of western Prince William Sound (PWS), Alaska, USA. Saffron cod have not been previously reported in PWS, and their capture suggests that fish community structure has changed in nearshore habitats. Nearly 16 000 saffron cod were captured in 49 of 95 beach seine hauls...

From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...

Commonly known as saffron, Crocus sativus L and its active components have shown several useful pharmacological effects such as anticonvulsant, antidepressant, anti-inflammatory, antitumor, radical scavenger effects, learning and memory improving effects, etc. There has been an increasing body of data on saffron use in medical databases within the last 20 years. In the current review, the stren...

BACKGROUND Crocus sativus L. (saffron), which belongs to the Iridaceae family, is widely cultivated in Iran. Cardiovascular effects of saffron has been established in some studies but the effects of chronic administration of saffron (C. sativus) stigma aqueous extract on blood pressure has not been investigated. OBJECTIVES In this study the effects of saffron (C. sativus) stigma aqueous extra...

From ancient times, the saffron Crocus sativus L. is widely used as drug to promote health and fight disease, especially in the Middle East and Southeast Asia. Saffron is cultivated in different parts of the world, but currently mainly in Iran. In view of its wide range of medical uses, the saffron has under gone extensive phytochemical and biochemical studies and variety of biologically active...

Saffron, obtained from the dried stigmas of Crocus sativus L., is an important spice, rich in carotenoids. Carotenoids are capable of protecting cells from the attack of free radicals, which naturally develop during sunbathing, smoking, exercise – even breathing oxygen. It has been estimated that our body needs 6 to 30 mg of carotenoids per day to protect its cells. These amounts are normally c...

Background: Saffron (Crocus satious L.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. Objective: Based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. Methods...