The economic and effective method for preparation of R-(-)-ibuprofen by diastereomer crystallization was developed. R-(-)-ibuprofen was resolved from racemic ibuprofen by forming R-(-)-ibuprofen-R-(+)-alpha-methylbenzylamine diastereomeric salt with R-(+)-alpha(-methylbenzylamine and crystallization. The purity of R-(-)-ibuprofen-R-(+)-alpha-methylbenzylamine diastereomeric salt was tested and ...

We study the influence of different surfactants on NaCl crystallization during evaporation of aqueous salt solutions. We found that at concentrations of sodium chloride close to saturation, only the cationic surfactant CTAB and the nonionic surfactant Tween 80 remain stable. For the nonionic surfactant, the high concentration of salt does not significantly change either the critical micellar co...

We report a real-time study on protein crystallization in the presence of multivalent salts using small angle X-ray scattering (SAXS) and optical microscopy, focusing particularly on the nucleation mechanism as well as on the role of the metastable intermediate phase (MIP). Using bovine beta-lactoglobulin as a model system in the presence of the divalent salt CdCl2, we have monitored the early ...

We demonstrated an approach to generate microscale branch-like salt crystallization patterns induced by a regular nanopillar array fabricated by using the laser interference lithography system. Branches of the inorganic salt crystals had similar shapes repeating at different sizes, ranging from ~ 1 m to 20 m in width, covering the 2×2 cm 2 area patterned with nanopillars. The angles between t...

Cholesterol crystallization is a key step in gallstone formation and is influenced by numerous factors. Human bile contains various bile salts having different hydrophobicity and micelle-forming capacities, but the importance of lipid composition to bile metastability remains unclear. This study investigated the effect of bile salts on cholesterol crystallization in model bile (MB) systems. Sup...

Magnesium sulfate salts have been linked to the decay of stone in the field and in laboratory experiments, but the mechanism of damage is still poorly understood. Thermomechanical analysis shows that expansion of stone contaminated with magnesium sulfate salts occurs during drying, followed by relaxation of the stress during dehydration of the precipitated salts. We applied thermogravimetric an...

The studies on the resistance to degradation of capillary polypropylene membranes assembled in a membrane crystallizer were performed. The supersaturation state of salt was achieved by evaporation of water from the NaCl saturated solutions using membrane distillation process. A high feed temperature (363 K) was used in order to enhance the degradation effects and to shorten the test times. Salt...

cazro3 nanoceramics were successfully synthesized at 700 c using the molten salt method, and the effects of processing parameters, such as temperature, holding time, and amount of salt on the crystallization of cazro3 were investigated. cacl2, na2co3, and nano-zro2 were used as starting materials. on heating, cacl2–nacl molten eutectic salt provided a liquid medium for the reaction of caco3 an...

Due to their widespread availability, sandstones are commonly used as a natural stone for buildings, monuments and sculptures. In thecurrent study, nine sandstone samples from the Upper Red Formation (specified by the letters A, B, C, CG, S, S1, Sh, Tr and Min)were studied from a petrophysical point of view and their durability was evaluated. Then, their suitability as building stones wasassess...

Suitable conditions for protein crystallization are commonly identified by screening combinations of independent factors that affect crystal formation. Because precipitating agents are prime determinants of crystallization, we investigated whether a systematic exploration of combinations of mechanistically distinct precipitants would enhance crystallization. A crystallization screen containing ...