نتایج جستجو برای: sapho

تعداد نتایج: 328  

Journal: :Clinical and experimental rheumatology 2008
Y Arnson A Rubinow H Amital

The SAPHO syndrome may evolve following low virulent infections. This report describes a patient who developed a clinical syndrome that complied with the formal diagnostic criteria of the SAPHO following an infection with syphilis. His clinical manifestations gradually resolved following antibiotic therapy. This interesting association underlines the pathogenic circumstances linking infections ...

Journal: :AJNR. American journal of neuroradiology 1999
K Marsot-Dupuch J E Doyen W O Grauer S C de Givry

We report a case of arthritis of the temporomandibular joint (TMJ) associated with sclerosing osteomyelitis of the mandible and temporal bone, causing deafness. The presence of a palmoplantar pustulosis established the diagnosis of SAPHO syndrome. SAPHO (an acronym referring to synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis) syndrome is defined by the association of charac...

2017
Yu Kamata Tomohiro Yamada Tomoki Sumida Hiroyuki Nakano Goro Sugiyama Azusa Nakashima Yoshihide Mori

SAPHO syndrome is a chronic disease of unknown etiology, which is characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis, however, pediatric osteomyelitis of the jawbone is rarely reported. We present a report of pediatric nonbacterial osteomyelitis of the mandible associated with SAPHO syndrome. A seven-year-old girl presented complaining of pain in, and swelling of, the righ...

2009
Koichiro Komiya Harumoto Yamada Nobuki Terada Yoshikazu Mizoguchi Mitsuko Yamada Masashi Suzuki Shinichi Kato

Introduction: Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disorder. The etiology remains unknown and the treatment is still empirical. Synovitis is one of the major manifestations, but information on histopathological features is still lacking. In this case, we investigated the histopathological features of SAPHO syndrome synovitis. Case presentation: We present t...

Journal: :WMJ : official publication of the State Medical Society of Wisconsin 2017
Chetan Sharma Brian Chow

Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is considered after exclusion of infection and arthritis; however, microbial infection may be present in osteoarticular lesions of these patients. Chronic osteomyelitis and associated bacterial infection were detected in a recurrent osteoarticular lesion in an adolescent patient with a history of clavicle pain, who complained of r...

Journal: :BMJ case reports 2016
Akira Baba Hiroya Ojiri Shinichi Takahashi Akira Katakura

To cite: Baba A, Ojiri H, Takahashi S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015213401 DESCRIPTIONF A 47-year-old man was referred to our hospital due to symptoms of trismus and exacerbation of palmoplantar pustulosis. He had been presenting, for 20 years, with refractory and recurrent mandibular osteomyelitis accompanied by palmoplantar pustulos...

2017
Shoichi Hasegawa Hiroki Yabe Naoya Kaneko Eri Watanabe Takahisa Gono Chihiro Terai

We herein report a rare case of a 66-year-old woman who had synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome with marked sternal osteitis and bilateral pleural effusions. SAPHO syndrome was diagnosed based on the characteristic features of a hyperostotic sternum and thoracic spine. The inflammatory changes of sternal osteitis and involvement of the adjacent soft tissue were assu...

2017
Hitoshi Amano Reikei Matsuda Tomohiko Shibata Daisuke Takahashi Shinichiro Suzuki

Currently, anti-TNFα antibodies are used to treat Crohn's disease. We report on a 45-year-old Japanese female with Crohn's disease developing SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome following exposure to the anti-TNFα antibody adalimumab. Initially, adalimumab induced remission, but the patient showed SAPHO syndrome 11 weeks following the start of adalimumab the...

Journal: :Rheumatology 2008
M Hurtado-Nedelec S Chollet-Martin P Nicaise-Roland S Grootenboer-Mignot R Ruimy O Meyer G Hayem

OBJECTIVE The aetiology of SAPHO (synovitis, acne, palmoplantar pustulosis, hyperostosis, osteitis) syndrome seems to involve genetic, infectious and immunological components. We examined innate and adaptive immune responses in SAPHO syndrome, as compared with PsA and RA. We also studied the effect of etanercept on immunological parameters. METHODS We studied 29 patients with SAPHO syndrome, ...

Journal: :The Open Rheumatology Journal 2009
C.E Huber A.G Judex J Freyschmidt S Feuerbach J Schölmerich U Müller-Ladner

The SAPHO syndrome represents a variety of clinically similar disorders with the key features of hyperostotic bone lesions in combination with chronic pustular skin disease. The respective pathophysiology of bone and joint manifestations in SAPHO syndrome is still a matter of discussion. For example it does not appear to represent reactive arthritis and HLA B27 antigen, with the latter being ty...

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