نتایج جستجو برای: schmidtea mediterranea

تعداد نتایج: 561  

Journal: :The International journal of developmental biology 2012
Alissa M Resch Dasaradhi Palakodeti

Planarians are bilaterally symmetrical fresh water organisms capable of regenerating body parts from small fragments following bodily injury. Planarians possess a specialized population of pluripotent cells called neoblasts, which are responsible for their unique regenerative ability. The study of planarian stem cell biology and regeneration has traditionally focused on the transcription factor...

Journal: :Molecules 2016
Cristiane Bezerra da Silva Arnildo Pott Selene Elifio-Esposito Luciane Dalarmi Kátia Fialho do Nascimento Ligia Moura Burci Maislian de Oliveira Josiane de Fátima Gaspari Dias Sandra Maria Warumby Zanin Obdulio Gomes Miguel Marilis Dallarmi Miguel

Dugesia tigrina is a non-parasitic platyhelminth, which has been recently utilized in pharmacological models, regarding the nervous system, as it presents a wide sensitivity to drugs. Our trials aimed to propose a model for an in vivo screening of substances with inhibitory activity of the enzyme acetylcholinesterase. Trials were performed with four drugs commercialized in Brazil: donepezil, ta...

2016
Ko W Currie Alyssa M Molinaro Bret J Pearson

The asexual freshwater planarian is a constitutive adult, whose central nervous system (CNS) is in a state of constant homeostatic neurogenesis. However, very little is known about the extrinsic signals that act on planarian stem cells to modulate rates of neurogenesis. We have identified two planarian homeobox transcription factors, Smed-nkx2.1 and Smed-arx, which are required for the maintena...

Journal: :Physical biology 2017
Xingbo Yang Kelson J Kaj David J Schwab Eva-Maria S Collins

Uncovering the mechanisms that control size, growth, and division rates of organisms reproducing through binary division means understanding basic principles of their life cycle. Recent work has focused on how division rates are regulated in bacteria and yeast, but this question has not yet been addressed in more complex, multicellular organisms. We have, over the course of several years, assem...

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