BACKGROUND We investigated the effect of polymorphisms in the renin-angiotensin-aldosterone system (RAAS) genes on ventricular remodeling, growth, renal function, and response to enalapril in infants with single ventricle. METHODS AND RESULTS Single ventricle infants enrolled in a randomized trial of enalapril were genotyped for polymorphisms in 5 genes: angiotensinogen, angiotensin-convertin...

Background—We investigated the effect of polymorphisms in the renin-angiotensin-aldosterone system (RAAS) genes on ventricular remodeling, growth, renal function, and response to enalapril in infants with single ventricle. Methods and Results—Single ventricle infants enrolled in a randomized trial of enalapril were genotyped for polymorphisms in 5 genes: angiotensinogen, angiotensin-converting ...

OBJECTIVE Currently, no quantitative guidelines have been established for treatment of left pulmonary artery (LPA) stenosis. This study aims to quantify the effects of LPA stenosis on postoperative hemodynamics for single-ventricle patients undergoing stage II superior cavopulmonary connection (SCPC) surgery, using a multiscale computational approach. METHODS Image data from 6 patients were s...

We present the use of a series of laboratory, analytical and interpretation methods to investigate personalized cancer care for a case of small cell prostate carcinoma (SCPC), a rare and aggressive tumor with poor prognosis, for which the underlying genomic architecture and mutational spectrum has not been well characterized. We performed both SNP genotyping and exome sequencing of a Virchow no...

PurposeSingle ventricular assist device (SVAD) support in with children single ventricle (SV) physiology remains challenging. We hypothesized that an individualized approach to SV patients—particularly those superior cavopulmonary connections (SCPCs)—including changing the “stage” of palliation at time VAD would promote improved outcomes.MethodsWe performed a single-center retrospective chart r...

The geometric interpretation of turbo decoding has founded a framework, and provided tools for the analysis of parallelconcatenated codes decoding. In this paper, we extend this analytical basis for the decoding of serially concatenated codes, and focus on serially concatenated product codes (SCPC) (i.e., product codes with checks on checks). For this case, at least one of the component (i.e., ...

In cystic fibrosis (CF), a lack of functional CF transmembrane conductance regulator (CFTR) chloride channels causes defective secretion by submucosal glands (SMGs), leading to persistent bacterial infection that damages airways and necessitates tissue repair. SMGs are also important niches for slow-cycling progenitor cells (SCPCs) in the proximal airways, which may be involved in disease-relat...

Heterogeneous semiconductor photoredox catalysis (SCPC), particularly with TiO2, is evolving to provide radically new synthetic applications. In this review we describe how photoactivated SCPCs can either (i) interact with a precursor that donates an electron to the semiconductor thus generating a radical cation; or (ii) interact with an acceptor precursor that picks up an electron with product...

A prototype self-centering prestressedconcrete (SCPC) bridge pier andconventional reinforced concrete (RC) with similar backbone curves are designed and modeled. The objective of this study is to investigate the seismic performance SCPC considering effect vertical earthquake ground motions. Under a severe motion, RC damage much greater than pier. shows great capability in reducing residual drif...

Submit Manuscript | http://medcraveonline.com Abbreviations: PSA: Prostate Specific Antigen; PET-CT: Positron Emission Tomography Computerized Tomography; SCPC: Small Cell Prostate Cancer; PCI: Prophylactic Cranial Irradiation; PC: Prostate Cancer; SCLC: Small Cell Lung Cancer; WHO: World Health Organization; CRPC: Castration-Resistant Prostate Cancer; ESCC: Extrapulmonary Small Cell Cancer; OS...