A diester prodrug of nalbuphine, sebacoyl dinalbuphine (SDN), and its long-acting formulation are currently being developed to prolong the duration of nalbuphine. A comparative in vitro hydrolysis study was conducted for SDN in rat, rabbit, dog, and human blood. Both SDN and nalbuphine in blood or plasma were measured by high-performance liquid chromatography. The hydrolysis rates of SDN in blo...

Software-Defined Networking (SDN) has the potential to automate and radically simplify management of computer networks—today a manual, error-prone task. Many networks however, especially enterprise networks, face a deployment problem: How to migrate an existing network to SDN? SDN must be introduced incrementally to build confidence and respect infrastructure budget constraints. In this article...

Software-defined networking (SDN) is being strongly considered as the next promising networking platform, and studies regarding SDN have been actively conducted accordingly. However, the security of SDN remains undefined and unknown when considering the enhancement of network security in SDN. In this paper, we verify whether SDN can enhance network security. Specifically, the idea of enabling s...

High-level programming and programmable data paths are two key capabilities of software-defined networking (SDN). A fundamental problem linking these two capabilities is whether a given high-level SDN program can be realized onto a given low-level SDN datapath structure. Considering all highlevel programs that can be realized onto a given datapath as the programming capacity of the datapath, we...

Although software-defined networking (SDN) brings numerous benefits by decoupling the control plane from the data plane, there is a contradictory relationship between SDN and distributed denial-of-service (DDoS) attacks. On one hand, the capabilities of SDN make it easy to detect and to react to DDoS attacks. On the other hand, the separation of the control plane from the data plane of SDN intr...

Mininet is network emulation software that allows launching a virtual network with switches, hosts and an SDN controller all with a single command on a single Linux kernel. It is a great way to start learning about SDN and Open-Flow as well as test SDN controller and SDN applications. Mininet can be used to deploy large networks on a single computer or virtual machine provided with limited reso...

Software Defined Networking (SDN) has emerged as a new network architecture for dealing with network dynamics through software-enabled control. While SDN is promoting many new network applications, security has become an important concern. This paper provides an extensive survey on SDN security. We discuss the security threats to SDN according to their effects, i.e., Spoofing, Tampering, Repudi...

Software defined networks (SDN) has been proposed to monitor and manage the communication networks globally. SDN revolutionized the way the communication network managed previously. By segregating the control plane from the data plane, SDN helps the network operators to manage the network flexibly. Since smart grid heavily relies on communication networks, therefore, SDN has also paved its way ...

Nowadays, Software Defined Network (SDN) architectures and applications are revolutionizing the way wired networks are built and operate. However, little is known about the potential of this disruptive technology in wireless mobile networks. In fact, SDN is based on a centralized network control principle, while existing mobile network protocols give emphasis on the distribution of network reso...

The new paradigm of Software-Defined Networking (SDN) enables exciting new functionality for building networks. Its core component is the so called SDN controller (also termed network operating system). An SDN controller is logically centralized and crucially important, thus, exploiting it can significantly harm SDN-based networks. As recent work considers only flaws and rudimentary malicious l...