The unique structures of human choriogonadotropin (hCG) and related glycoprotein hormones make them well suited for studies of protein folding in the endoplasmic reticulum. hCG is stabilized by a strand of its beta-subunit that has been likened to a "seatbelt" because it surrounds alpha-subunit loop 2 and its end is "latched" by an intrasubunit disulfide bond to the beta-subunit core. As shown ...

conclusions the seatbelt wearing rate among the study participants was much lower than the 90% rate reported among iranian drivers in 2010. mandating seatbelt use, as in most countries, will be more effective if a combination of factors such as changes in vehicle design, road safety, and driver and passenger behavior are taken into account. background seatbelts are a relatively low-cost safety ...

Computed tomography angiography (CTA) of the neck has become the most common modality for diagnosing blunt carotid artery injury (BCAI). The protocol at our institution includes CTA on trauma patients with a seatbelt sign. The purpose of this study is to evaluate whether a solitary seatbelt sign is an indication for CTA of the neck to diagnose BCAI. We conducted a retrospective review of patien...

Modification of seatbelts and their legislation played an important role in reducing morbidity and mortality of occupants in road traffic collisions. We aimed to review seatbelt development, its mechanism of action and its effects. Seatbelts reduce injury by preventing the occupant from hitting the interior parts of the vehicle or being ejected from the car. We have made a linear regression cor...

Typical seatbelt designs can interfere with police officers operational work by lengthening their response time in threatening situations. Therefore, in certain operational circumstances there is a direct conflict between operational safety (effective response to threat) and driving safety (seatbelt use). To evaluate this potential conflict, 341 police officers from the southeastern US complete...

Seatbelt and airbag are included in most of the vehicles as safety devices to reduce the severity of injury and costs of motor vehicle crashes. The aim of this paper is to study the effectiveness of these two restraints in the UAE based on comparing the observed injuries and fatalities for occupants. This will help identifying most life threating combinations and as such forming policies to red...

Most current seatbelt load limiter technologies could only offer three or fewer predetermined patterns of seatbelt restraint force. However, researches have shown that, to better realize adaptive protection to different occupants under different crash severities, a continuously and real-time adjustable load limiter may be one step further. This concept could be especially favorable to vulnerabl...

BACKGROUND Injuries and deaths from road traffic collisions present an enormous challenge to the South African (SA) healthcare system. The use of restraining devices is an important preventive measure. OBJECTIVE To determine the relationship between seatbelt use and injury severity in vehicle occupants involved in road traffic collisions in Cape Town, SA. METHODS A prospective cohort design...

The seatbelt syndrome describes an injury pattern infrequently seen in restrained passengers in motor vehicle collisions. It occurs when sudden deceleration forces coupledwith compression of the lap belt around the abdomen causes abdominalwall bruising, intra-abdominal injuries, and spinal fractures. Infrequent and improper use of appropriate belt restraints in children has led to high risks fo...