A recent large-scale retrospective study has revealed that the frequency and aggressiveness of extraocular sebaceous carcinoma is comparable with that of the periocular counterpart (1) and a signiflcant number of extraocular sebaceous carcinomas show regional and widespread métastases (2). However, sentinel lymph node (SLN) biopsy has seldom been used for identifying regional nodal metastasis i...

Sebaceous carcinoma is a very rare and potentially aggressive carcinoma originating from the epithelial lining of the sebaceous gland. More than 70% of all cases are in the head and neck region, especially the periorbita; therefore, they are classified into ocular and extraocular sebaceous carcinoma. The reported risk factors are advanced age, male sex, previous irradiation, and genetic predisp...

BACKGROUND Sebaceous cell carcinoma of the eyelid is a malignant tumor. However, the pathoetiology of sebaceous cell carcinoma is not clear. Retinoic acid (RA) signaling is essential for skin epidermal differentiation including the eyelids. In this study, we investigate the expression of β-catenin, RA-binding proteins and RA receptors in sebaceous cell carcinoma of the eyelid and try to estimat...

Abstrac: Sebaceous gland carcinoma is a rare and fast-growing, potentially lethal skin malignant tumor originating from the adnexal epithelium of sebaceous glands. This more common in superior palpebral than inferior ratio 3:1 elderly with predilection for women. Because it clinically similar to chalazion or chronic inflammatory condition that can cause delays diagnosis. this rarity, we report ...

Although carcinoma in situ has been accepted as a well-established concept and diagnostic category, for reasons unknown sebaceous carcinoma in situ has not been recognized yet in general pathology or dermatopathology. Such lesions have always been misinterpreted as either benign neoplasm or sebaceous carcinoma. In the present essay, we provide a convincing account supporting sebaceous carcinoma...

Sebaceous cell carcinoma of the skin is a rare malignancy of the skin appendages. Most commonly noticed in the orbital region. Extra orbital sebaceous cell carcinoma is extremely rare. The aggressive behavior of this tumor is still a matter of controversy. We present a case of sebaceous cell carcinoma in scalp region in young women.

BACKGROUND Sebaceous carcinoma is notorious for masquerading clinically as other benign lesions such as chalazion. A tool to better differentiate between these two conditions would thus be desirable. PURPOSE To examine the potential application of noninvasive meibography in the differential diagnosis of chalazion and sebaceous carcinoma of the eyelid as a retrospective cross-sectional study. ...

BACKGROUND Sebaceous glands contribute significantly to the barrier functions of the skin. However, little is known about their homeostasis and tumorigenesis. Recently, increased expression of stem cell marker Lrig1 has been reported in sebaceous carcinoma-like tumors of K14ΔNLef1 transgenic mice. In this study, we analyzed the Lrig1 expression in human sebaceous tumors. METHODS Twenty-eight ...

Sebaceous carcinoma (SC) is a rare cutaneous malignant neoplasm. It derived from the epithelium of sebaceous glands and thus, can occur anywhere in body where these are found. SC two types: ocular extraocular, with extraocular being axilla very rare. The paper reports case 55-year-old male patient, complain swelling right axilla. patient underwent wide local excision mass excised specimen was s...

Sebaceous carcinoma is a rare malignant tumor differentiated from the adnexal epithelium of sebaceous glands and forms less than 1% of all cutaneous malignancies. We present a case of a 93-year-old woman with a rapidly growing mass on the right cheek. Initial histiopathologic finding was basal cell carcinoma. The mass was widely excised and superficial parotidectomy was performed while preservi...