Objectives: Cetuximab is an anticancerous drug which causes oral mucositis as a major side effect. Oral mucositis can be reduced by the effect of grape seed extract which modulates the inflammatory pathways. Our aim is to evaluate the effect of Grape seed extract and Cetuximab drug on mucositis and bacterial infection in tongue mucosa of experimental rats. Design: 24 rats were housed in the ani...

the oxidative stability of margarine supplemented with different concentrations of fennel (foeniculum vulgare) seed extract (fse) was compared to the synthetic antioxidants; butylated hydroxyanisole (bha) and butylated hydroxytoluene (bht) at legal concentrations. the experiment was carried out under accelerated storage conditions for 4 weeks employing peroxide value (pv), p-anisidine value (av...

An extract of a rotenone-containing plant yam bean, Pachyrhizus erosus (L.) Urban, seeds was tested against the diamondback moth, Plutella xylostella (L.) in a greenhouse to determine its potential as an oviposition deterrent and compared with coumarin and rutin, known as diamondback moth oviposition deterrent compounds, rotenone, and an extract of Peruvian cube root, at a concentration of 0.5%...

The effects of grape seeds extract and grape peels extract prepared from grape pomace on the activity of antioxidant enzymes, degree of lipid peroxidation in serum and liver tissue were investigated in rabbits fed on high cholesterol diet. New Zealand white rabbits were divided as follows ; 1) NOR (normal group); 2) CHOL (cholesterol group); 3) GSH (cholesterol + grape seed extract group); 4) G...

Cassia fistula seeds have many therapeutic uses in traditional medicine practice. The present investigation was undertaken to demonstrate the anticandidal activity of the C. fistula seed extract at ultra-structural level through transmission electron microscope (TEM) and scanning electron microscope (SEM) observations. The effect of seed extract on the growth profile of the Candida albicans was...

OBJECTIVE Mucositis is a serious disorder of the gastrointestinal tract that results from cancer chemotherapy. We investigated the effects of increasing grape seed extract doses on the severity of chemotherapy in a rat model and its coincident impact on chemotherapeutic effectiveness in colon cancer cells. DESIGN Female Dark Agouti rats were gavaged with grape seed extract (400-1000 mg/kg) or...

The experiment was conducted to find out the efficacy of dodder vine extract as seed protectant against pulse beetle, Callosobruchus chinensis on gram seed in the laboratory of the Department of Entomology, Bangladesh Agricultural University, Mymensingh during the period of February to May, 2009. The concentrations of dodder vine extract were 5, 2 and 1% respectively. Efficacies of these treatm...

The hawthorn fruits have been used as food and medicine for centuries. In the present study, pulp and seed extract of Crataegus elbursensis Rech. F. fruits belonging to the family Rosaceae and native of northern part of Iran were evaluated for the polyphenol contents, antiradical, antioxidant, and antibacterial activities. The total phenolic, flavonoid, and anthocyanin contents of methanolic pu...

We screened for α-glucosidase inhibitors from 12 traditional medicinal plants used for the treatment of diabetes. Potent α-glucosidase inhibitory activity was found in aqueous extract of Psidium guajava leaves and Syzygium cumini Linn seed extract. Active principles inhibiting α-glucosidase were isolated and identified as apigenin 7O-glucoside in the S.cumini Linn seed extract and Dihydro-3,3’,...

The therapeutic potential of Cassia surattensis in reducing free radical-induced oxidative stress and inflammation particularly in hepatic diseases was evaluated in this study. The polyphenol rich C. surattensis seed extract showed good in vitro antioxidant. C. surattensis seed extract contained total phenolic content of 100.99 mg GAE/g dry weight and there was a positive correlation (r > 0.9) ...