The senseless (sens) gene is required for proper development of most cell types of the embryonic and adult peripheral nervous system (PNS) of Drosophila. Sens is a nuclear protein with four Zn fingers that is expressed and required in the sensory organ precursors (SOP) for proper proneural gene expression. Ectopic expression of Sens in many ectodermal cells causes induction of PNS external sens...

~. Le probl~me central de la linguistique est congu comme la construction d'un module fonctionnel (susceptible d'etre r~alis~ sous forme d'un programme pour ordinateur) du langage, c'est-~-dire, d'un syst~me qui transforme n'importe quel sens donn~ en textes correspondants ou vice-versa. Partant du fait fondamental qu'en parlant on ne fait qu'exprimer un contenu pr~congu, le module ici pr~sent~...

Senseless (Sens) is a conserved transcription factor required for normal development of the Drosophila peripheral nervous system. In the Drosophila retina, sens is necessary and sufficient for differentiation of R8 photoreceptors and interommatidial bristles (IOBs). When Sens is expressed in undifferentiated cells posterior to the morphogenetic furrow, ectopic IOBs are formed. This phenotype wa...

OBJECTIVE To compare the ability of the simple erosion narrowing score (SENS) to classify radiographic progression relative to the Sharp/van der Heijde score (SHS) in a prospective cohort of anti-TNF-treated RA patients. METHODS Radiographs of the hands, wrists and feet of patients enrolled in a pharmacovigilance programme are performed every 2 years. These radiographs were read in chronologi...